174684

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2381104..2381288 Replicon chromosome
Accession NZ_CP062372
Organism Staphylococcus aureus strain NAS_AN_109

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag IF710_RS11750 Protein ID WP_000482650.1
Coordinates 2381181..2381288 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2381104..2381164 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF710_RS11735 (IF710_11675) 2376614..2376781 - 168 WP_001792506.1 hypothetical protein -
IF710_RS11740 (IF710_11680) 2377012..2378745 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
IF710_RS11745 (IF710_11685) 2378770..2380533 - 1764 WP_001064820.1 ABC transporter ATP-binding protein -
- 2381104..2381164 + 61 - - Antitoxin
IF710_RS11750 (IF710_11690) 2381181..2381288 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
IF710_RS11755 (IF710_11695) 2381422..2381808 - 387 WP_000779358.1 flippase GtxA -
IF710_RS11760 (IF710_11700) 2382066..2383208 + 1143 WP_001176863.1 glycerate kinase -
IF710_RS11765 (IF710_11705) 2383268..2383927 + 660 WP_000831298.1 membrane protein -
IF710_RS11770 (IF710_11710) 2384109..2385320 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
IF710_RS11775 (IF710_11715) 2385443..2385916 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T174684 WP_000482650.1 NZ_CP062372:c2381288-2381181 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T174684 NZ_CP081347:21441-21716 [Pseudomonas aeruginosa]
ATGGAGTTGAAGTGGACGAGCAAAGGGCTCTCCGACGTGGCACGGCTCTACGAGTTCCTGGCTACGGTGAACAGGGAAGC
TGCCGCCCGCACGGTGCAGCAGCTGACGAGCGCGCCGACCGCCTTGTTGACCAACCCGCGGCTGGGCGAGCGCCTGGAAG
AGTTCGAACCGCGGGATGTTCGCCGCATCCTGATCGGCCACTATGAGATGCGCTATGAGATCCTGGATTCCTGCATCTAC
GTGCTTCGTCTGTGGCACACACGCGAAGACAGGTAG

Antitoxin


Download         Length: 61 bp

>AT174684 NZ_CP062372:2381104-2381164 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References