Detailed information of TA system TA174629

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 222710..222892
• Replicon: chromosome
• Accession: NZ_CP062366
• Organism: Staphylococcus aureus strain NAS_AN_123

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF713_RS01440
• Protein ID: WP_001801861.1
• Coordinates: 222797..222892 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	222710..222769 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF713_RS01425	221848..222225	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IF713_RS01430	222419..222595	+	177	Protein_248	transposase	-
IF713_RS01435	222573..222674	-	102	WP_001791893.1	hypothetical protein	-
-	222710..222769	+	60	-	-	Antitoxin
IF713_RS01440	222797..222892	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF713_RS01445	223095..223238	+	144	WP_001549059.1	transposase	-
IF713_RS01450	223842..224225	+	384	WP_000070811.1	hypothetical protein	-
IF713_RS01455	224236..224412	+	177	WP_000375476.1	hypothetical protein	-
IF713_RS01460	224414..224599	+	186	WP_000809857.1	hypothetical protein	-
IF713_RS01465	224713..225354	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IF713_RS01470	225572..226123	-	552	WP_000414205.1	hypothetical protein	-
IF713_RS01475	226221..226565	-	345	WP_000627551.1	DUF3969 family protein	-
IF713_RS01480	226606..227232	-	627	Protein_258	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	202794..248918	46124

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174629 WP_001801861.1 NZ_CP062366:c222892-222797 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174629 NZ_CP081306:340532-341059 [Escherichia coli]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT174629 NZ_CP062366:222710-222769 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin