Detailed information of TA system TA174536

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 169230..169410
• Replicon: chromosome
• Accession: NZ_CP062354
• Organism: Staphylococcus aureus strain NAS_AN_206

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF730_RS01060
• Protein ID: WP_001801861.1
• Coordinates: 169315..169410 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	169230..169287 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF730_RS01030	165581..166699	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
IF730_RS01035	167347..167790	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
IF730_RS01040	168018..168347	+	330	WP_223294405.1	DUF1433 domain-containing protein	-
IF730_RS01045	168369..168743	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
IF730_RS01050	168931..169113	+	183	Protein_171	transposase	-
IF730_RS01055	169091..169192	-	102	WP_001791232.1	hypothetical protein	-
-	169230..169287	+	58	-	-	Antitoxin
IF730_RS01060	169315..169410	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF730_RS01065	169861..170307	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
IF730_RS01070	170992..171375	+	384	WP_000070811.1	hypothetical protein	-
IF730_RS01075	171386..171562	+	177	WP_240021887.1	hypothetical protein	-
IF730_RS01080	171862..172490	+	629	Protein_177	ImmA/IrrE family metallo-endopeptidase	-
IF730_RS01085	172688..173260	-	573	Protein_178	hypothetical protein	-
IF730_RS01090	173361..173702	-	342	WP_000627548.1	DUF3969 family protein	-
IF730_RS01095	173743..174369	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	132381..195227	62846

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174536 WP_001801861.1 NZ_CP062354:c169410-169315 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174536 NZ_CP081187:c4204386-4204102 [Salmonella enterica]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTTGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT174536 NZ_CP062354:169230-169287 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin