Detailed information of TA system TA174500

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 175372..175552
• Replicon: chromosome
• Accession: NZ_CP062350
• Organism: Staphylococcus aureus strain NAS_AN_250

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF736_RS01080
• Protein ID: WP_001801861.1
• Coordinates: 175457..175552 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	175372..175429 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF736_RS01055	170981..172246	+	1266	WP_000072555.1	restriction endonuclease subunit S	-
IF736_RS01060	172285..173132	+	848	Protein_173	DNA adenine methylase	-
IF736_RS01065	173110..173730	+	621	WP_225970474.1	hypothetical protein	-
IF736_RS01070	173721..174806	+	1086	WP_001808016.1	hypothetical protein	-
IF736_RS01075	175236..175334	-	99	Protein_176	hypothetical protein	-
-	175372..175429	+	58	-	-	Antitoxin
IF736_RS01080	175457..175552	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF736_RS01085	176004..176450	+	447	WP_000747805.1	DUF1433 domain-containing protein	-
IF736_RS01090	176564..177190	+	627	Protein_179	ImmA/IrrE family metallo-endopeptidase	-
IF736_RS01095	177322..178074	-	753	WP_000764922.1	staphylococcal enterotoxin type 27	-
IF736_RS01100	178101..178784	-	684	WP_000957233.1	exotoxin beta-grasp domain-containing protein	-
IF736_RS01105	178871..179497	-	627	WP_000669028.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	154095..182055	27960

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174500 WP_001801861.1 NZ_CP062350:c175552-175457 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174500 NZ_CP081016:c2977570-2977295 [Pseudomonas sp. 2hn]
ATGGACTTGAAGTGGACCAGCAAGGCGCTCTCTGATATTGCCCGACTGTATGAGTTTCTTGCGGCGGTCAATAAACCGGC
TGCCGTGAGAACCGTCCAGCAGCTCACCGGCGCTGCCTCCATGCTCTTGGCCAATCCGCGTATCGGTGAACGCCTGGAAG
AGTTCGAACCACGGGATGTGCGCCGGATCCAGATCGGCCACTATGAGATGCGTTACGAGATAGCGGACTCCACGCTCTTC
CTGCTGCGGCTCTGGCACACCCGTGAGGATCGGTAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT174500 NZ_CP062350:175372-175429 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin