Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1554478..1554660 Replicon chromosome
Accession NZ_CP062348
Organism Staphylococcus aureus strain NAS_AN_260

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF738_RS07590 Protein ID WP_001801861.1
Coordinates 1554478..1554573 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1554601..1554660 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF738_RS07555 1550148..1550774 + 627 WP_000669017.1 hypothetical protein -
IF738_RS07560 1550815..1551156 + 342 WP_000627541.1 DUF3969 family protein -
IF738_RS07565 1551257..1551829 + 573 WP_000414202.1 hypothetical protein -
IF738_RS07570 1552027..1552655 - 629 Protein_1490 ImmA/IrrE family metallo-endopeptidase -
IF738_RS07575 1552958..1553134 - 177 WP_000375477.1 hypothetical protein -
IF738_RS07580 1553145..1553528 - 384 WP_000070811.1 hypothetical protein -
IF738_RS07585 1554132..1554275 - 144 WP_001549059.1 transposase -
IF738_RS07590 1554478..1554573 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1554601..1554660 - 60 - - Antitoxin
IF738_RS07595 1554696..1554797 + 102 WP_001791893.1 hypothetical protein -
IF738_RS07600 1554775..1554951 - 177 Protein_1496 transposase -
IF738_RS07605 1555145..1555522 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T174480 WP_001801861.1 NZ_CP062348:1554478-1554573 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T174480 NZ_CP062348:1554478-1554573 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT174480 NZ_CP062348:c1554660-1554601 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References