Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2652493..2652772 | Replicon | chromosome |
Accession | NZ_CP062346 | ||
Organism | Staphylococcus aureus strain NAS_AN_261 |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | IF739_RS13080 | Protein ID | WP_001802298.1 |
Coordinates | 2652493..2652597 (+) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF3 | ||
Locus tag | - | ||
Coordinates | 2652593..2652772 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IF739_RS13055 | 2647902..2648684 | + | 783 | WP_240017953.1 | ABC transporter ATP-binding protein | - |
IF739_RS13060 | 2648752..2649609 | + | 858 | WP_000370936.1 | HAD family hydrolase | - |
IF739_RS13070 | 2650658..2651785 | + | 1128 | WP_047213687.1 | SAP domain-containing protein | - |
IF739_RS13075 | 2651892..2652332 | + | 441 | Protein_2538 | recombinase family protein | - |
IF739_RS13080 | 2652493..2652597 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
- | 2652593..2652772 | - | 180 | - | - | Antitoxin |
IF739_RS13090 | 2653103..2654194 | - | 1092 | WP_047213685.1 | hypothetical protein | - |
IF739_RS13095 | 2654460..2655440 | - | 981 | WP_000019739.1 | CDF family zinc efflux transporter CzrB | - |
IF739_RS13100 | 2655442..2655762 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
IF739_RS13105 | 2655914..2656579 | + | 666 | WP_001024091.1 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T174473 WP_001802298.1 NZ_CP062346:2652493-2652597 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T174473 NZ_CP081010:1919083-1919337 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 180 bp
>AT174473 NZ_CP062346:c2652772-2652593 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGTAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT
GTGTTAAAATATATTTGTAGTAAGTAGAAGTAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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