Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2652493..2652772 Replicon chromosome
Accession NZ_CP062346
Organism Staphylococcus aureus strain NAS_AN_261

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag IF739_RS13080 Protein ID WP_001802298.1
Coordinates 2652493..2652597 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2652593..2652772 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF739_RS13055 2647902..2648684 + 783 WP_240017953.1 ABC transporter ATP-binding protein -
IF739_RS13060 2648752..2649609 + 858 WP_000370936.1 HAD family hydrolase -
IF739_RS13070 2650658..2651785 + 1128 WP_047213687.1 SAP domain-containing protein -
IF739_RS13075 2651892..2652332 + 441 Protein_2538 recombinase family protein -
IF739_RS13080 2652493..2652597 + 105 WP_001802298.1 hypothetical protein Toxin
- 2652593..2652772 - 180 - - Antitoxin
IF739_RS13090 2653103..2654194 - 1092 WP_047213685.1 hypothetical protein -
IF739_RS13095 2654460..2655440 - 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
IF739_RS13100 2655442..2655762 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
IF739_RS13105 2655914..2656579 + 666 WP_001024091.1 SDR family oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T174473 WP_001802298.1 NZ_CP062346:2652493-2652597 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T174473 NZ_CP081010:1919083-1919337 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 180 bp

>AT174473 NZ_CP062346:c2652772-2652593 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGTAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References