Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2639767..2640045 Replicon chromosome
Accession NZ_CP062344
Organism Staphylococcus aureus strain NAS_AN_265

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag IF740_RS13085 Protein ID WP_001802298.1
Coordinates 2639767..2639871 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 2639867..2640045 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF740_RS13070 2636564..2637346 + 783 WP_000908175.1 ABC transporter ATP-binding protein -
IF740_RS13075 2637414..2638271 + 858 WP_000370926.1 HAD family hydrolase -
IF740_RS13080 2638929..2639087 - 159 WP_001792784.1 hypothetical protein -
IF740_RS13085 2639767..2639871 + 105 WP_001802298.1 hypothetical protein Toxin
- 2639867..2640045 - 179 - - Antitoxin
IF740_RS13095 2640313..2641404 - 1092 WP_000495671.1 lytic regulatory protein -
IF740_RS13100 2641670..2642650 - 981 WP_239794322.1 CDF family zinc efflux transporter CzrB -
IF740_RS13105 2642652..2642972 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
IF740_RS13110 2643124..2643789 + 666 WP_001024093.1 SDR family oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T174457 WP_001802298.1 NZ_CP062344:2639767-2639871 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T174457 NZ_CP081009:c3913171-3912917 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 179 bp

>AT174457 NZ_CP062344:c2640045-2639867 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9


Antitoxin

Download structure file

References