Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2304591..2304775 Replicon chromosome
Accession NZ_CP062338
Organism Staphylococcus aureus strain NAS_NP_103

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag IF745_RS11225 Protein ID WP_072467491.1
Coordinates 2304591..2304698 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2304715..2304775 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF745_RS11200 2299964..2300437 + 474 WP_000456489.1 GyrI-like domain-containing protein -
IF745_RS11205 2300560..2301771 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
IF745_RS11210 2301953..2302612 - 660 WP_000831298.1 membrane protein -
IF745_RS11215 2302672..2303814 - 1143 WP_001176873.1 glycerate kinase -
IF745_RS11220 2304071..2304457 + 387 WP_000779348.1 flippase GtxA -
IF745_RS11225 2304591..2304698 + 108 WP_072467491.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2304715..2304775 - 61 - - Antitoxin
IF745_RS11230 2305288..2307051 + 1764 WP_001064834.1 ABC transporter ATP-binding protein -
IF745_RS11235 2307076..2308809 + 1734 WP_000486502.1 ABC transporter ATP-binding protein -
IF745_RS11240 2309040..2309207 + 168 WP_031866196.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 3944.67 Da        Isoelectric Point: 10.4934

>T174397 WP_072467491.1 NZ_CP062338:2304591-2304698 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Download         Length: 108 bp

>T174397 NZ_CP081007:2761876-2761979 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT174397 NZ_CP062338:c2304775-2304715 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References