Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1804717..1804933 Replicon chromosome
Accession NZ_CP062336
Organism Staphylococcus aureus strain NAS_NP_161

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag IF748_RS08945 Protein ID WP_001802298.1
Coordinates 1804829..1804933 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 1804717..1804772 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF748_RS08920 1799753..1800073 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
IF748_RS08925 1800075..1801055 + 981 WP_000019739.1 CDF family zinc efflux transporter CzrB -
IF748_RS08930 1801321..1802412 + 1092 WP_000495672.1 hypothetical protein -
IF748_RS08935 1802441..1804087 - 1647 WP_000277718.1 IS1182 family transposase -
- 1804717..1804772 + 56 - - Antitoxin
IF748_RS08945 1804829..1804933 - 105 WP_001802298.1 hypothetical protein Toxin
IF748_RS08950 1805613..1805771 + 159 WP_001792784.1 hypothetical protein -
IF748_RS08955 1806430..1807287 - 858 WP_240029689.1 HAD family hydrolase -
IF748_RS08960 1807355..1808137 - 783 WP_000908174.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1802441..1804087 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T174380 WP_001802298.1 NZ_CP062336:c1804933-1804829 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T174380 NZ_CP062336:c1804933-1804829 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT174380 NZ_CP062336:1804717-1804772 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References