Detailed information of TA system TA174341

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 179878..180060
• Replicon: chromosome
• Accession: NZ_CP062331
• Organism: Staphylococcus aureus strain NAS_OP_017

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF760_RS01085
• Protein ID: WP_001801861.1
• Coordinates: 179965..180060 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	179878..179937 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF760_RS01070	179016..179393	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IF760_RS01075	179587..179763	+	177	Protein_177	transposase	-
IF760_RS01080	179741..179842	-	102	WP_001791893.1	hypothetical protein	-
-	179878..179937	+	60	-	-	Antitoxin
IF760_RS01085	179965..180060	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF760_RS01090	180263..180406	+	144	WP_001549059.1	transposase	-
IF760_RS01095	181010..181393	+	384	WP_000070811.1	hypothetical protein	-
IF760_RS01100	181404..181580	+	177	WP_000375476.1	hypothetical protein	-
IF760_RS01105	181582..181767	+	186	WP_000809857.1	hypothetical protein	-
IF760_RS01110	181881..182522	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IF760_RS01115	182740..183291	-	552	WP_240021560.1	hypothetical protein	-
IF760_RS01120	183389..183733	-	345	WP_000627551.1	DUF3969 family protein	-
IF760_RS01125	183774..184400	-	627	Protein_187	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	146789..206085	59296

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174341 WP_001801861.1 NZ_CP062331:c180060-179965 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174341 NZ_CP080960:4714979-4715266 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGTAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT174341 NZ_CP062331:179878-179937 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin