Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2565867..2566129 Replicon chromosome
Accession NZ_CP062329
Organism Staphylococcus aureus strain NAS_OP_026

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag IF761_RS12570 Protein ID WP_001802298.1
Coordinates 2565867..2565971 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2565966..2566129 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF761_RS12550 2562664..2563446 + 783 WP_000908189.1 ABC transporter ATP-binding protein -
IF761_RS12555 2563514..2564371 + 858 WP_000370928.1 HAD family hydrolase -
IF761_RS12560 2565029..2565187 - 159 WP_001792784.1 hypothetical protein -
IF761_RS12565 2565180..2565350 - 171 WP_001792292.1 transposase -
IF761_RS12570 2565867..2565971 + 105 WP_001802298.1 hypothetical protein Toxin
- 2565966..2566129 - 164 - - Antitoxin
IF761_RS12580 2566470..2567561 - 1092 WP_000495681.1 hypothetical protein -
IF761_RS12585 2567827..2568807 - 981 WP_000019743.1 CDF family zinc efflux transporter CzrB -
IF761_RS12590 2568809..2569129 - 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
IF761_RS12595 2569281..2569946 + 666 WP_001024095.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T174330 WP_001802298.1 NZ_CP062329:2565867-2565971 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T174330 NZ_CP080960:1071120-1071222 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 164 bp

>AT174330 NZ_CP062329:c2566129-2565966 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References