Detailed information of TA system TA174295

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 223577..223759
• Replicon: chromosome
• Accession: NZ_CP062324
• Organism: Staphylococcus aureus strain NAS_OP_063

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF767_RS01445
• Protein ID: WP_001801861.1
• Coordinates: 223664..223759 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	223577..223636 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF767_RS01430	222715..223092	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
IF767_RS01435	223286..223462	+	177	Protein_249	transposase	-
IF767_RS01440	223440..223541	-	102	WP_001791893.1	hypothetical protein	-
-	223577..223636	+	60	-	-	Antitoxin
IF767_RS01445	223664..223759	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF767_RS01450	223962..224105	+	144	WP_001549059.1	transposase	-
IF767_RS01455	224709..225092	+	384	WP_000070811.1	hypothetical protein	-
IF767_RS01460	225103..225279	+	177	WP_000375476.1	hypothetical protein	-
IF767_RS01465	225281..225466	+	186	WP_000809857.1	hypothetical protein	-
IF767_RS01470	225580..226221	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
IF767_RS01475	226439..226990	-	552	WP_000414205.1	hypothetical protein	-
IF767_RS01480	227088..227432	-	345	WP_000627551.1	DUF3969 family protein	-
IF767_RS01485	227473..228099	-	627	Protein_259	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	205057..261199	56142

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174295 WP_001801861.1 NZ_CP062324:c223759-223664 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174295 NZ_CP080635:c308810-308511 [Shewanella putrefaciens]
ATGAAAAATAAACGCTATAAACTGAGTAAGTTAGCTCAAACTCACTTACTAAAGATTAAAGACTACACCATTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAAGAAAGCCTAATATCCGGCTTGCAAATGTTAGCCGATAACCCCGGATTAGGCA
GAAGCTGCGAAGATATTTACCCCAACGGATTCTACTTTCCGATTGCTAAACACACCGCCTACTTCACAAAAGAAGACGAC
TTCATCCTCATCGTTGCCATGTTAGGCCAGCCACAACTACCACAAAATCATCTGAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT174295 NZ_CP062324:223577-223636 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin