Detailed information of TA system TA174282

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2348427..2348611
• Replicon: chromosome
• Accession: NZ_CP062322
• Organism: Staphylococcus aureus strain NAS_OP_071

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: IF768_RS11555
• Protein ID: WP_072467491.1
• Coordinates: 2348427..2348534 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2348551..2348611 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF768_RS11530	2343800..2344273	+	474	WP_000456489.1	GyrI-like domain-containing protein	-
IF768_RS11535	2344396..2345607	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
IF768_RS11540	2345789..2346448	-	660	WP_000831298.1	membrane protein	-
IF768_RS11545	2346508..2347650	-	1143	WP_001176873.1	glycerate kinase	-
IF768_RS11550	2347907..2348293	+	387	WP_000779348.1	flippase GtxA	-
IF768_RS11555	2348427..2348534	+	108	WP_072467491.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2348551..2348611	-	61	-	-	Antitoxin
IF768_RS11560	2349124..2350887	+	1764	WP_001064834.1	ABC transporter ATP-binding protein	-
IF768_RS11565	2350912..2352645	+	1734	WP_000486502.1	ABC transporter ATP-binding protein	-
IF768_RS11570	2352876..2353043	+	168	WP_031866196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3944.67 Da
• Isoelectric Point: 10.4934

>T174282 WP_072467491.1 NZ_CP062322:2348427-2348534 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

>T174282 NZ_CP080627:707817-708080 [Halomonas qaidamensis]
ATGAGTAGTCGTTTACTGTCATGGACTGACGAATCCTGGAGCGATTACCTGTATTGGCAAACCCAGGACAAAAAAACGCT
GAAACGAATAAACAAGCTTATAAACGACGCTAGACGCTCACCCTTTGAAGGTATTGGTAAACCAGAGCCGTTAAAGGAAA
ACTTAGCTGGTTTTTGGTCGCGACGTATAGATGATACGAATCGATTAGTCTACGCAGTTGATGATAATGCGATTACGATC
ATTTCGTGTCGTTATCACTATTAG

Antitoxin

Nucleotide

• Length: 61 bp

>AT174282 NZ_CP062322:c2348611-2348551 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin