Detailed information of TA system TA174245

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2296821..2297005
• Replicon: chromosome
• Accession: NZ_CP062318
• Organism: Staphylococcus aureus strain NAS_OP_132

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: IF775_RS11180
• Protein ID: WP_072467491.1
• Coordinates: 2296821..2296928 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2296945..2297005 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF775_RS11155	2292194..2292667	+	474	WP_000456489.1	GyrI-like domain-containing protein	-
IF775_RS11160	2292790..2294001	-	1212	WP_001192075.1	multidrug effflux MFS transporter	-
IF775_RS11165	2294183..2294842	-	660	WP_000831298.1	membrane protein	-
IF775_RS11170	2294902..2296044	-	1143	WP_001176873.1	glycerate kinase	-
IF775_RS11175	2296301..2296687	+	387	WP_000779348.1	flippase GtxA	-
IF775_RS11180	2296821..2296928	+	108	WP_072467491.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	2296945..2297005	-	61	-	-	Antitoxin
IF775_RS11185	2297518..2299281	+	1764	WP_001064834.1	ABC transporter ATP-binding protein	-
IF775_RS11190	2299306..2301039	+	1734	WP_000486502.1	ABC transporter ATP-binding protein	-
IF775_RS11195	2301270..2301437	+	168	WP_031866196.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3944.67 Da
• Isoelectric Point: 10.4934

>T174245 WP_072467491.1 NZ_CP062318:2296821-2296928 [Staphylococcus aureus]
IFNLLIDIMTSAISGCLVAFFANWLRTRSNKKGDK

Nucleotide

• Length: 108 bp

>T174245 NZ_CP080599:c1754844-1754587 [Nocardiopsis sp. MT53]
GTGACCTACAGGACGATCTTCCGCCCCGAGGCCCGGGAGGAGCTGCGCAAGCTGCCCCGCACCGTGGCCATGAGCGTGTT
CCGCAAACTGACCGAACTGGAGGCCGACCCTCTGGGCTTCGGCACCACGGCCCTGGTCGGCTCTCCCGAGGTGCGACGCC
TCAGAGTGGGCGACTACCGGGTCATCTACACCGTGGAGCACGACCGGCTCATCGTGTGGGTCGTCCATGTGGGGCACCGC
TCCGGCGTCTACGACTGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT174245 NZ_CP062318:c2297005-2296945 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Antitoxin