Detailed information of TA system TA174241

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 164993..165173
• Replicon: chromosome
• Accession: NZ_CP062318
• Organism: Staphylococcus aureus strain NAS_OP_132

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: IF775_RS01045
• Protein ID: WP_001801861.1
• Coordinates: 165078..165173 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	164993..165050 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IF775_RS01015	161344..162462	+	1119	WP_000072558.1	restriction endonuclease subunit S	-
IF775_RS01020	163110..163553	+	444	WP_000742594.1	DUF1433 domain-containing protein	-
IF775_RS01025	163832..164110	+	279	WP_001798632.1	DUF1433 domain-containing protein	-
IF775_RS01030	164132..164506	+	375	WP_000695818.1	DUF1433 domain-containing protein	-
IF775_RS01035	164694..164876	+	183	Protein_168	transposase	-
IF775_RS01040	164854..164955	-	102	WP_001791232.1	hypothetical protein	-
-	164993..165050	+	58	-	-	Antitoxin
IF775_RS01045	165078..165173	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
IF775_RS01050	165624..166070	+	447	WP_000747802.1	DUF1433 domain-containing protein	-
IF775_RS01055	166755..167138	+	384	WP_000070811.1	hypothetical protein	-
IF775_RS01060	167149..167325	+	177	WP_000375476.1	hypothetical protein	-
IF775_RS01065	167625..168253	+	629	Protein_174	ImmA/IrrE family metallo-endopeptidase	-
IF775_RS01070	168451..169023	-	573	Protein_175	hypothetical protein	-
IF775_RS01075	169124..169465	-	342	WP_000627548.1	DUF3969 family protein	-
IF775_RS01080	169506..170132	-	627	WP_000669019.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	hlgA / lukD	145200..190990	45790

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T174241 WP_001801861.1 NZ_CP062318:c165173-165078 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T174241 NZ_CP080597:c3690896-3690645 [Pseudomonas sp. ERGC3:05]
GTGTCAAAAAATGAAAAGCTGCTCGCCAAACTGCTCAACGAGCACATGGCCTTTACCTGGCCAGAGCTCGTAACGCTGCT
GCATCGCTTGGGCTACACACAGATTGAAGGGGCTGGAAGCCGCGTCAAGTTCGACATCGGCGACCCCAGTGCAATGATCA
GCTTGCACAAGCCTCACCCCGGCAACGAACTGAAACACTACATTCGGCGCCAGATCATCGAACAATTGAAATCAGGAGAA
CTGATTCAGTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT174241 NZ_CP062318:164993-165050 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin