Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2384566..2385083 Replicon chromosome
Accession NZ_CP062312
Organism Staphylococcus aureus strain NAS_OP_163

Toxin (Protein)


Gene name yoeB Uniprot ID T1YC79
Locus tag IF782_RS11760 Protein ID WP_000113262.1
Coordinates 2384817..2385083 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID T1YB60
Locus tag IF782_RS11755 Protein ID WP_000584499.1
Coordinates 2384566..2384817 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10437.95 Da        Isoelectric Point: 9.9143

>T174212 WP_000113262.1 NZ_CP062312:2384817-2385083 [Staphylococcus aureus]
MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALEGIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDNHIK
IASCKYHY

Download         Length: 267 bp

>T174212 NZ_CP080590:c258301-257984 [Devosia salina]
ATGCCCCAGGGTGACAAGAGCGCCTATACCGACAAGCAGAAGCGCAAGGCCGAGCATATCGAGGAGCGTTACGAGGATCG
TGGCGTATCGCATAAGGAGGCCGAGCGGCGCGCCTGGGCCACCGTCAACAAGGATGATGGCGGCGGCAACAAGTCCGGCT
CCGGACGCGGCACGCACAAAGATCATCCTGCCGCCCACAAGGGTGGCAAGAAGGGCGGCGAAGCCTCGGCCAATCGGCCC
GCATCGGAGCGCTCAGCTTCCGCAAAAAAGGCCGCCGCAACCCGCAAGCGGAACCAAGAGCACCACGCGCATCACTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9433.60 Da        Isoelectric Point: 4.3407

>AT174212 WP_000584499.1 NZ_CP062312:2384566-2384817 [Staphylococcus aureus]
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKD
IDV

Download         Length: 252 bp

>AT174212 NZ_CP080590:c257974-257111 [Devosia salina]
ATGTCCGGCTCGGCCGCCAAGCCCATGAACCCGCCCCAGACCCAGGACCATCAGCCGGGGCGGGAAAGCGAAATGCATCC
CAAGCCCGATTACATGCCGAAATTCCCCGGCAATGGGCGCCTCAAGGACAAGGTCGCCATCATCACCGGTGGCGATAGCG
GGATCGGGCGTGCCTGCGCCGTCCTCTTTGCCCGTGAAGGGGCCGAGGTGGCGCTGGTCTATCTCGAAGAGACCGATGAC
GCGAGGCTCACTGCCGAGGCCGTCAAGGCGGAGGGCAAGGAGGCGCTGCTGCTGCGCGGCGATGTCAGCGACAAGGCGGT
TTGCGAGAGTGTGGTCGGCCAGGTGGTCGAAAAATTCGGCAAGCTCGATGTGCTGGTCAACAACGCGGCCGAGCAGCATA
TGCAGACCGAGCTCGAGGCCATTTCCGAAGAGCAGTTGCGGCGCACCTTCGAGACCAATTTCTTTGGCTATATGTTCATG
ACGCAGGCCGCGCTGCCGCATCTGAGAAAGGGGTCGGCGATCGTCAACACGACATCGATCACGGCCTATCGGGGCTCGCC
GTCACTGATGGATTATGCCGCGACCAAGGGCGCCATCGTCGCCTTTACCCGATCGCTCTCGGAAAGCCTTGCCGGCAAGG
GTATCCGCGTCAATGGCGTCGCACCCGGCCCGATCTGGACGCCGCTGATCCCGGCCAGTTTCCCGGCCGACAAGGTGGCG
GAATTCGGGGCCAGCCAGCCATTGGGCCGGCCGGGCCAGCCCAATGAGGTGGCAACGAGCCACCTGTTCCTCGCCTGCGA
AGAGAGTTCCTACATCACCGGGCAGGTGCTGCACCCCAATGGCGGGGAGATCATCGGGGGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 6L8G
PDB 6L8F
PDB 7CUA
PDB 6L8E

Antitoxin

Source ID Structure
PDB 6L8G
PDB 6L8F
PDB 7BWF
PDB 6L8E
AlphaFold DB T1YB60

References