Detailed information of TA system TA174170

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/HigB-HigA
• Location: 5657403..5657983
• Replicon: chromosome
• Accession: NZ_CP062253
• Organism: Pseudomonas gozinkensis strain IzPS32d

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: IHQ43_RS25200
• Protein ID: WP_192562476.1
• Coordinates: 5657403..5657681 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: IHQ43_RS25205
• Protein ID: WP_045121630.1
• Coordinates: 5657696..5657983 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-1 (3-92)

Antitoxin

• Cro/C1-type helix-turn-helix domain (20-75)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10719.30 Da
• Isoelectric Point: 8.9401

>T174170 WP_192562476.1 NZ_CP062253:5657403-5657681 [Pseudomonas gozinkensis]
MIKSFQHKGLRGFYETGSTRGIRADHAKRLSRMLQFMDRAAVPGDLDLPGWRMHPLKGELCEYWSLSVSGNWRVIFRFAG
SDIELIDYLDYH

Nucleotide

• Length: 279 bp

>T174170 NZ_CP080564:c2160179-2160075 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10542.17 Da
• Isoelectric Point: 6.9219

>AT174170 WP_045121630.1 NZ_CP062253:5657696-5657983 [Pseudomonas gozinkensis]
MPMHNPPHPGETLLMDVLPELGISVTELARHLGFARPHLSRVLHGHAPISPDLAVRLERAGIGKARMWLGVQTDYDLWQA
EHREQPAIQPIAAHA

Nucleotide

• Length: 288 bp

>AT174170 NZ_CP080564:2159982-2160020 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC