Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5381870..5382525 Replicon chromosome
Accession NZ_CP062253
Organism Pseudomonas gozinkensis strain IzPS32d

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IHQ43_RS23905 Protein ID WP_065261338.1
Coordinates 5382181..5382525 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IHQ43_RS23900 Protein ID WP_007956715.1
Coordinates 5381870..5382184 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ43_RS23875 5377383..5377901 - 519 WP_192562334.1 peptide-methionine (R)-S-oxide reductase MsrB -
IHQ43_RS23880 5378053..5378769 + 717 WP_192562335.1 response regulator transcription factor -
IHQ43_RS23885 5378766..5380286 + 1521 WP_192562336.1 HAMP domain-containing histidine kinase -
IHQ43_RS23890 5380407..5381111 + 705 WP_192562337.1 hypothetical protein -
IHQ43_RS23895 5381181..5381672 - 492 WP_007956714.1 RidA family protein -
IHQ43_RS23900 5381870..5382184 - 315 WP_007956715.1 helix-turn-helix domain-containing protein Antitoxin
IHQ43_RS23905 5382181..5382525 - 345 WP_065261338.1 toxin Toxin
IHQ43_RS23910 5382651..5383538 - 888 WP_039765651.1 heme o synthase -
IHQ43_RS23915 5383549..5383884 - 336 WP_007956718.1 cytochrome o ubiquinol oxidase subunit IV -
IHQ43_RS23920 5383884..5384510 - 627 WP_007956720.1 cytochrome o ubiquinol oxidase subunit III -
IHQ43_RS23925 5384514..5386544 - 2031 WP_192562338.1 cytochrome o ubiquinol oxidase subunit I -
IHQ43_RS23930 5386548..5387489 - 942 WP_085606895.1 ubiquinol oxidase subunit II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13444.31 Da        Isoelectric Point: 9.2890

>T174169 WP_065261338.1 NZ_CP062253:c5382525-5382181 [Pseudomonas gozinkensis]
MRTVFFETTLFTANLGHYLTDDEYRELQTYMQSNPHAGDVMPRTGGFRKLRWVDVRRGKGRRGGLRVIYYWLMNDGQFWM
FAIYDKDELENLTAEQEKALKGAIEKELKTRGTP

Download         Length: 345 bp

>T174169 NZ_CP080564:c2101702-2101493 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11859.77 Da        Isoelectric Point: 10.3048

>AT174169 WP_007956715.1 NZ_CP062253:c5382184-5381870 [Pseudomonas gozinkensis]
MKKRDLFAELMQGVDEMAAQREGKITLRNTTLEDKPAPEVGAQEIVALREKLHMSQAVFARRIRTSPSTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLSAV

Download         Length: 315 bp

>AT174169 NZ_CP080564:c2102007-2101714 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References