Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4184492..4185147 Replicon chromosome
Accession NZ_CP062252
Organism Pseudomonas allokribbensis strain IzPS23

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag IF199_RS19100 Protein ID WP_096822369.1
Coordinates 4184492..4184836 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IF199_RS19105 Protein ID WP_007951468.1
Coordinates 4184833..4185147 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF199_RS19085 4180588..4182120 + 1533 WP_096822265.1 NADH-quinone oxidoreductase subunit M -
IF199_RS19090 4182128..4183591 + 1464 WP_102622478.1 NADH-quinone oxidoreductase subunit NuoN -
IF199_RS19095 4183658..4184122 - 465 WP_192558403.1 GNAT family N-acetyltransferase -
IF199_RS19100 4184492..4184836 + 345 WP_096822369.1 toxin Toxin
IF199_RS19105 4184833..4185147 + 315 WP_007951468.1 transcriptional regulator Antitoxin
IF199_RS19110 4185307..4186632 + 1326 WP_192558404.1 OprD family porin -
IF199_RS19115 4186784..4187116 - 333 WP_192560980.1 DUF2790 domain-containing protein -
IF199_RS19120 4187196..4187396 - 201 WP_096822271.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13569.38 Da        Isoelectric Point: 6.9816

>T174160 WP_096822369.1 NZ_CP062252:4184492-4184836 [Pseudomonas allokribbensis]
MDALFIELPAFQKHRDDYLDDDLFRSFQLELLKNPEAGDLIEGTGGLRKIRFCDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKNEQDDLLPSQKRVFKQALDTEINTRTQI

Download         Length: 345 bp

>T174160 NZ_CP080562:c2223014-2222652 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11913.79 Da        Isoelectric Point: 9.9898

>AT174160 WP_007951468.1 NZ_CP062252:4184833-4185147 [Pseudomonas allokribbensis]
MKRDIFSELMEGLEALADERQGKVTLRTHKVQLPKLLPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIDHLAALT

Download         Length: 315 bp

>AT174160 NZ_CP080562:c2223181-2223011 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References