Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2778788..2779347 Replicon chromosome
Accession NZ_CP062231
Organism Rhizobium sp. TH2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IHQ71_RS13920 Protein ID WP_258162539.1
Coordinates 2778788..2779075 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IHQ71_RS13925 Protein ID WP_258162540.1
Coordinates 2779072..2779347 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IHQ71_RS13885 (IHQ71_13845) 2773974..2774924 - 951 WP_258162532.1 nucleoside hydrolase -
IHQ71_RS13890 (IHQ71_13850) 2775015..2775410 - 396 WP_258162533.1 cobalamin biosynthesis protein -
IHQ71_RS13895 (IHQ71_13855) 2775414..2776334 - 921 WP_258162534.1 hypothetical protein -
IHQ71_RS13900 (IHQ71_13860) 2776477..2777262 + 786 WP_258162535.1 TSUP family transporter -
IHQ71_RS13905 (IHQ71_13865) 2777352..2777627 + 276 WP_258162536.1 type II toxin-antitoxin system ParD family antitoxin -
IHQ71_RS13910 (IHQ71_13870) 2777672..2778091 - 420 WP_258162537.1 helix-turn-helix domain-containing protein -
IHQ71_RS13915 (IHQ71_13875) 2778154..2778786 - 633 WP_258162538.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
IHQ71_RS13920 (IHQ71_13880) 2778788..2779075 - 288 WP_258162539.1 Txe/YoeB family addiction module toxin Toxin
IHQ71_RS13925 (IHQ71_13885) 2779072..2779347 - 276 WP_258162540.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IHQ71_RS13930 (IHQ71_13890) 2779382..2783095 - 3714 WP_258162541.1 cobaltochelatase subunit CobN -
IHQ71_RS13935 (IHQ71_13895) 2783157..2784206 - 1050 WP_258162542.1 cobalamin biosynthesis protein CobW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11558.30 Da        Isoelectric Point: 9.7883

>T173625 WP_258162539.1 NZ_CP062231:c2779075-2778788 [Rhizobium sp. TH2]
VRLCWSSRAWLDYIHWQQADWQYIEKINALIKDTMRNPFTGLGKPEPLRGEMQGLWSRRISGEHRFIYRVYGRGEDQTLE
VLFCRFHYVLPDRKK

Download         Length: 288 bp

>T173625 NZ_CP080253:2387974-2389296 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10318.55 Da        Isoelectric Point: 4.5416

>AT173625 WP_258162540.1 NZ_CP062231:c2779347-2779072 [Rhizobium sp. TH2]
MSYVNVSDFRQNLAAHLDEVENSRAPLFVTRNNRKAIVVMSEEEYESMMETLHLTSNPANAQLLRESIAEMNAGKLVEHD
IVERKDAEAAQ

Download         Length: 276 bp

>AT173625 NZ_CP080253:2387708-2387974 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References