Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1576034..1576550 Replicon chromosome
Accession NZ_CP062196
Organism Plesiomonas shigelloides strain P5462

Toxin (Protein)


Gene name yoeB Uniprot ID R8AQQ6
Locus tag IHE26_RS06850 Protein ID WP_010863491.1
Coordinates 1576281..1576550 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID R8AQQ5
Locus tag IHE26_RS06845 Protein ID WP_010863490.1
Coordinates 1576034..1576288 (+) Length 85 a.a.

Genomic Context

IHE26_RS06835IHE26_RS06840IHE26_RS06845IHE26_RS06850IHE26_RS06825IHE26_RS06830IHE26_RS06855IHE26_RS06860IHE26_RS06865IHE26_RS06870
Location: 1573275..1573622 (348 bp)
Type: Others
Protein ID: WP_192437668.1
Location: 1575071..1575826 (756 bp)
Type: Others
Protein ID: WP_192437670.1
Location: 1576034..1576288 (255 bp)
Type: Antitoxin
Protein ID: WP_010863490.1
Location: 1576281..1576550 (270 bp)
Type: Toxin
Protein ID: WP_010863491.1
Location: 1571296..1571592 (297 bp)
Type: Others
Protein ID: WP_192437666.1
Location: 1572095..1572556 (462 bp)
Type: Others
Protein ID: WP_192437923.1
Location: 1576813..1577277 (465 bp)
Type: Others
Protein ID: WP_192437672.1
Location: 1577691..1578335 (645 bp)
Type: Others
Protein ID: WP_192437674.1
Location: 1579348..1580046 (699 bp)
Type: Others
Protein ID: WP_039044680.1
Location: 1580578..1581042 (465 bp)
Type: Others
Protein ID: WP_192437676.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
IHE26_RS068251571296..1571592-297WP_192437666.1YkgJ family cysteine cluster protein-
IHE26_RS068301572095..1572556-462WP_192437923.1lecithin retinol acyltransferase family protein-
IHE26_RS068351573275..1573622+348WP_192437668.1cupin domain-containing protein-
IHE26_RS068401575071..1575826+756WP_192437670.1abortive infection family protein-
IHE26_RS068451576034..1576288+255WP_010863490.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
IHE26_RS068501576281..1576550+270WP_010863491.1Txe/YoeB family addiction module toxinToxin
IHE26_RS068551576813..1577277-465WP_192437672.1ASCH domain-containing protein-
IHE26_RS068601577691..1578335-645WP_192437674.1hypothetical protein-
IHE26_RS068651579348..1580046-699WP_039044680.1hypothetical protein-
IHE26_RS068701580578..1581042-465WP_192437676.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic islandqnrVC4-1541277..162217280895
-insideIntegron--1553059..158424231183


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10689.14 Da        Isoelectric Point: 6.9482

>T173475 WP_010863491.1 NZ_CP062196:1576281-1576550 [Plesiomonas shigelloides]
MSERLLCWTDESWDDYIYWQSQDKKTLKRINKLIIDVKRTPFEGIGKPEALRENLSGFWSRRIDDTNRLVYAVDDLSITI
ISCRYHYQA

Download         Length: 270 bp

>T173475 NZ_CP080223:c3852354-3851956 [Escherichia coli O141:H4]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9510.70 Da        Isoelectric Point: 5.6706

>AT173475 WP_010863490.1 NZ_CP062196:1576034-1576288 [Plesiomonas shigelloides]
MRIVSFTEARNSLKSVLDSVVNDADTTIITRRDADDAVVMSLDYYNSLMETVHLLRSPANAEHLNRSIAQFKAGRVTQRE
LKDE

Download         Length: 255 bp

>AT173475 NZ_CP080223:c3852650-3852357 [Escherichia coli O141:H4]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBR8AQQ6

Antitoxin

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Source
ID
Structure
AlphaFold DBR8AQQ5

References