Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 2748106..2748806 Replicon chromosome
Accession NZ_CP062158
Organism Pseudomonas lundensis strain 2T.2.5.2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag IF654_RS12755 Protein ID WP_047275766.1
Coordinates 2748106..2748402 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7Y1ASW6
Locus tag IF654_RS12760 Protein ID WP_047275764.1
Coordinates 2748405..2748806 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF654_RS12730 2744536..2745084 - 549 WP_194862389.1 hypothetical protein -
IF654_RS12735 2745086..2745358 - 273 WP_194862388.1 hypothetical protein -
IF654_RS12740 2745813..2746340 - 528 WP_194862387.1 lysis system i-spanin subunit Rz -
IF654_RS12745 2746337..2746882 - 546 WP_194862386.1 glycoside hydrolase family 19 protein -
IF654_RS12750 2746929..2747975 - 1047 WP_194862385.1 late control protein -
IF654_RS12755 2748106..2748402 + 297 WP_047275766.1 type II toxin-antitoxin system MqsR family toxin Toxin
IF654_RS12760 2748405..2748806 + 402 WP_047275764.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
IF654_RS12765 2748803..2749009 - 207 WP_047275762.1 tail protein X -
IF654_RS12770 2748984..2749829 - 846 WP_047275760.1 phage tail protein -
IF654_RS12775 2749846..2752878 - 3033 WP_194862384.1 phage tail tape measure protein -
IF654_RS12780 2753027..2753335 - 309 WP_047275756.1 phage tail assembly protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2738146..2818897 80751


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Zinc finger, MqsA-type

(3-47)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10822.65 Da        Isoelectric Point: 8.9282

>T173427 WP_047275766.1 NZ_CP062158:2748106-2748402 [Pseudomonas lundensis]
MEKKTPHCKLHTVKALIEAGKVRSTLSALTGGAALGFDFDGIVSVVMALAPADFYKSMTTHADHKVWQDVYRRKTQAGEV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T173427 NZ_CP080172:c1789821-1789714 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14492.60 Da        Isoelectric Point: 6.2235

>AT173427 WP_047275764.1 NZ_CP062158:2748405-2748806 [Pseudomonas lundensis]
MKCPSCVSAELVHDTRDVPYTYKNESTVIPSVTGEFCPACGETVLDASESTRVSAAMLAFNKQVNASIVDPGFITTVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTKPPLALVKLLKLLDHHPELLNEVRLG

Download         Length: 402 bp

>AT173427 NZ_CP080172:1789869-1789935 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y1ASW6

References