Detailed information of TA system TA173134

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2140466..2140683
• Replicon: chromosome
• Accession: NZ_CP061870
• Organism: Bacillus subtilis strain FX-1

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: IE382_RS11195
• Protein ID: WP_017696861.1
• Coordinates: 2140507..2140683 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2140466..2140566 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IE382_RS11180 (2136282)	2136282..2137184	-	903	WP_003230984.1	GIY-YIG nuclease family protein	-
IE382_RS11185 (2137369)	2137369..2139243	-	1875	Protein_2150	DNA-directed RNA polymerase YonO	-
IE382_RS11190 (2139283)	2139283..2139477	-	195	WP_041336994.1	hypothetical protein	-
- (2140466)	2140466..2140566	-	101	NuclAT_2	-	Antitoxin
- (2140466)	2140466..2140566	-	101	NuclAT_2	-	Antitoxin
- (2140466)	2140466..2140566	-	101	NuclAT_2	-	Antitoxin
- (2140466)	2140466..2140566	-	101	NuclAT_2	-	Antitoxin
IE382_RS11195 (2140507)	2140507..2140683	+	177	WP_017696861.1	hypothetical protein	Toxin
IE382_RS11200 (2140702)	2140702..2140952	+	251	Protein_2153	hypothetical protein	-
IE382_RS11205 (2140997)	2140997..2141185	+	189	WP_004399547.1	hypothetical protein	-
IE382_RS11210 (2141267)	2141267..2142499	+	1233	WP_041336993.1	hypothetical protein	-
IE382_RS11215 (2142839)	2142839..2144710	+	1872	WP_041336992.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2067902..2217296	149394

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6878.45 Da
• Isoelectric Point: 12.8833

>T173134 WP_017696861.1 NZ_CP061870:2140507-2140683 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKIRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T173134 NZ_CP080116:c3012493-3012029 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGATGCTTTAGTTGC
CGAAGTCGAGGCATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGTAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT173134 NZ_CP061870:c2140566-2140466 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin