Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4592535..4593235 Replicon chromosome
Accession NZ_CP061723
Organism Pseudomonas putida strain ZXPA-20

Toxin (Protein)


Gene name mqsR Uniprot ID A0A8I0Z9R5
Locus tag ID616_RS21075 Protein ID WP_060519866.1
Coordinates 4592939..4593235 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A8I0Z3K6
Locus tag ID616_RS21070 Protein ID WP_024717924.1
Coordinates 4592535..4592936 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ID616_RS21050 4587677..4588493 - 817 Protein_4135 transporter substrate-binding domain-containing protein -
ID616_RS21055 4588569..4589498 - 930 WP_016488289.1 FAD-binding protein -
ID616_RS21060 4589499..4590248 - 750 WP_016488290.1 electron transfer flavoprotein subunit beta/FixA family protein -
ID616_RS21065 4590782..4592464 + 1683 WP_080641073.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
ID616_RS21070 4592535..4592936 - 402 WP_024717924.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
ID616_RS21075 4592939..4593235 - 297 WP_060519866.1 type II toxin-antitoxin system MqsR family toxin Toxin
ID616_RS21080 4593330..4594655 - 1326 WP_060519867.1 MFS transporter -
ID616_RS21085 4594728..4595207 - 480 WP_023048065.1 hypothetical protein -
ID616_RS21090 4595507..4595968 + 462 WP_023048064.1 azurin -
ID616_RS21095 4596006..4596506 - 501 WP_095116961.1 sigma-70 family RNA polymerase sigma factor -
ID616_RS21100 4596737..4597918 + 1182 WP_031312009.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11175.10 Da        Isoelectric Point: 9.0375

>T172844 WP_060519866.1 NZ_CP061723:c4593235-4592939 [Pseudomonas putida]
MEKRTPHCPLERVKVLAAARRISPTGAALRGARALGMDYPGMLEVISCLERTDFYKSMTSHMDHRVWQDVYRPLTAFGYV
YLKVSVVDDVLIVSFKEL

Download         Length: 297 bp

>T172844 NZ_CP079991:c2500260-2499973 [Escherichia coli]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14516.57 Da        Isoelectric Point: 4.7550

>AT172844 WP_024717924.1 NZ_CP061723:c4592936-4592535 [Pseudomonas putida]
MRCPVCGGAELAPDVQGMPYSYKGEATVIPDVSGDYCCACGECVLSHDEAMRVSNLMTAFERQVNAAVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT172844 NZ_CP079991:c2500499-2500260 [Escherichia coli]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGTGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAATCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References