Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2379918..2380432 Replicon chromosome
Accession NZ_CP061539
Organism Rothia terrae strain KJZ-14

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IDM49_RS10820 Protein ID WP_190724514.1
Coordinates 2379918..2380175 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IDM49_RS10825 Protein ID WP_190724515.1
Coordinates 2380178..2380432 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IDM49_RS10805 2375575..2377056 - 1482 WP_190724512.1 hypothetical protein -
IDM49_RS10810 2377068..2378546 - 1479 WP_190725495.1 AAA family ATPase -
IDM49_RS10815 2378641..2379732 - 1092 WP_190724513.1 Fic family protein -
IDM49_RS10820 2379918..2380175 - 258 WP_190724514.1 Txe/YoeB family addiction module toxin Toxin
IDM49_RS10825 2380178..2380432 - 255 WP_190724515.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IDM49_RS10830 2380737..2381888 - 1152 WP_190725496.1 divalent metal cation transporter -
IDM49_RS10835 2382333..2383460 + 1128 WP_190724516.1 C4-dicarboxylate ABC transporter substrate-binding protein -
IDM49_RS10840 2383737..2385239 - 1503 WP_190724517.1 YdiU family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10342.83 Da        Isoelectric Point: 10.1925

>T172736 WP_190724514.1 NZ_CP061539:c2380175-2379918 [Rothia terrae]
MKIVWSENAWEDYLWWQGQDRRVLKRINLLIKDIQRNGNEGIGKPEALRNNLSGYWSRRITKEHRIVYKIVDDSIRIAAV
RYHYE

Download         Length: 258 bp

>T172736 NZ_CP079891:3676047-3676337 [Escherichia fergusonii]
ATGAACTATGAACTGGCTTTTGATCCGCGGGCGCTGAAAGAGTGGCAAAAACTGGGCGTGACAGTCCGGGAACAATTTAA
AAAAAAGCTTGGGGATGTGCTGAAAAGGCCGCGCAATCCATCGGCTAAACTACGGGATTTGCCGGACTGCTACAAAATTA
AGCTTCGCACACTGGGATATCGCCGGGTCTATCAGGTCAATGATAAAGAGTTACTCGTGTTGGTGATAGCTATTGGTAAG
AGAGAGAACTCAGCCGTTTATGAAGACGCGACAAAACGGCTGGATGAGTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9453.53 Da        Isoelectric Point: 4.1532

>AT172736 WP_190724515.1 NZ_CP061539:c2380432-2380178 [Rothia terrae]
MKTLTYTESRARYAEVLDSVVNDCEEVVVTRAGREPAVILSLAEYESLKETAYLLRSPVNARRLFDSISELENDGGAERD
LLED

Download         Length: 255 bp

>AT172736 NZ_CP079891:3675815-3676057 [Escherichia fergusonii]
ATGGCCACACTTAACGTCCGCCTGGATGACAAACTGAAAAATGAGGCTTATGCGGTGCTGGAAAAATTAAATATCACGCC
TACTGAAGCAGTGCGGCTGCTGTTTCAGTACATTGCGGAAAATGGACGAATGCCGGTAAAAACGCTCACTGTCAGTGATA
GTGAAGAAGCCTTGTTACGCACTGTCAGGGAACGACTGGCCAACCCACAGGAGGCCATTAAGGTCCGACTGGATGAACTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References