Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3359946..3360535 Replicon chromosome
Accession NZ_CP061375
Organism Xanthomonas oryzae pv. oryzae strain IXO608

Toxin (Protein)


Gene name graT Uniprot ID A0A8E2YMU3
Locus tag IXO608_RS15750 Protein ID WP_011260747.1
Coordinates 3359946..3360227 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag IXO608_RS15755 Protein ID WP_011260746.1
Coordinates 3360245..3360535 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO608_RS15745 (IXO608_015615) 3357599..3359851 + 2253 WP_044756263.1 exodeoxyribonuclease V subunit alpha -
IXO608_RS15750 (IXO608_015620) 3359946..3360227 + 282 WP_011260747.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO608_RS15755 (IXO608_015625) 3360245..3360535 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
IXO608_RS15760 (IXO608_015630) 3361474..3362868 + 1395 WP_011260745.1 type III secretion system effector XopQ -
IXO608_RS15765 3362971..3363158 - 188 Protein_3012 hypothetical protein -
IXO608_RS15770 (IXO608_015635) 3363318..3363650 - 333 WP_011260743.1 hypothetical protein -
IXO608_RS15775 (IXO608_015640) 3363905..3364210 + 306 WP_230455549.1 hypothetical protein -
IXO608_RS15780 (IXO608_015645) 3364360..3364782 + 423 WP_033013301.1 PAAR domain-containing protein -
IXO608_RS15785 (IXO608_015650) 3364785..3365261 + 477 WP_011260741.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11038.77 Da        Isoelectric Point: 10.2139

>T172514 WP_011260747.1 NZ_CP061375:3359946-3360227 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQQRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T172514 NZ_CP079772:3052962-3053339 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCACGCCCGTCTCCGGTTGAAATCTGGCAGACACTGCTCAC
CCGACTGCTGGATCAGCACTACGGCCTTACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGCGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGTTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCACGCCGGGCAACCGGCCTGATGACACGCGA
CAACTACAGAACGGTAAATAACATTACCCTGGGTAAACATCCGGGGGCGAAACAATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT172514 WP_011260746.1 NZ_CP061375:3360245-3360535 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT172514 NZ_CP079772:3052504-3052872 [Escherichia coli]
GTGTCAGACAAACTCCATGAGACAAATTATCCCGACGACCATAACGACCGCCTCTGGTGGGGACTGCTCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGTCGACCGCGCCGGCATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAGCTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References