Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 537104..537611 Replicon chromosome
Accession NZ_CP061312
Organism Polynucleobacter sp. AP-Sving-400A-A2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag C2758_RS02870 Protein ID WP_215329502.1
Coordinates 537351..537611 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag C2758_RS02865 Protein ID WP_215306249.1
Coordinates 537104..537361 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C2758_RS02850 (C2758_02845) 533219..534061 + 843 WP_215330043.1 formate dehydrogenase accessory sulfurtransferase FdhD -
C2758_RS02855 (C2758_02850) 534103..534669 + 567 WP_215329500.1 dCTP deaminase -
C2758_RS02860 (C2758_02855) 534718..536985 + 2268 WP_215329501.1 arginine/lysine/ornithine decarboxylase -
C2758_RS02865 (C2758_02860) 537104..537361 + 258 WP_215306249.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
C2758_RS02870 (C2758_02865) 537351..537611 + 261 WP_215329502.1 Txe/YoeB family addiction module toxin Toxin
C2758_RS02875 (C2758_02870) 537632..539164 - 1533 WP_215329503.1 TRAP transporter large permease subunit -
C2758_RS02880 (C2758_02875) 539161..539712 - 552 WP_215329504.1 TRAP transporter small permease subunit -
C2758_RS02885 (C2758_02880) 539718..541136 - 1419 WP_215329505.1 argininosuccinate lyase -
C2758_RS02890 (C2758_02885) 541180..542160 + 981 WP_215329506.1 hydroxymethylbilane synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10202.67 Da        Isoelectric Point: 8.8692

>T172328 WP_215329502.1 NZ_CP061312:537351-537611 [Polynucleobacter sp. AP-Sving-400A-A2]
MLSRVVWTSASWSDYVYWQGQDKKTLRRINALIKDAMRNPEDGIGKPEELKESLSGFWSRRIDDVHRLVYAIEKDQLVVI
ACRYHY

Download         Length: 261 bp

>T172328 NZ_CP079735:184820-184927 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9683.04 Da        Isoelectric Point: 7.1645

>AT172328 WP_215306249.1 NZ_CP061312:537104-537361 [Polynucleobacter sp. AP-Sving-400A-A2]
MRVINFSDARNQFKQVIDQVVSDCDVAIISRRDADDAVVMSLNTYNSMMETLHLLKSPANVKHLEKSLAQYRKGQTKEKN
LVDAE

Download         Length: 258 bp

>AT172328 NZ_CP079735:c184772-184706 [Escherichia coli]
GGTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References