Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 410386..410896 Replicon chromosome
Accession NZ_CP061298
Organism Polynucleobacter paludilacus strain MWH-Mekk-C3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag AOC06_RS02340 Protein ID WP_215380914.1
Coordinates 410633..410896 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag AOC06_RS02335 Protein ID WP_215380913.1
Coordinates 410386..410643 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AOC06_RS02300 (AOC06_02300) 405496..405939 - 444 WP_215380907.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
AOC06_RS02305 (AOC06_02305) 405966..406355 - 390 Protein_448 ribosome silencing factor -
AOC06_RS02310 (AOC06_02310) 406391..407080 - 690 WP_215380910.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
AOC06_RS02315 (AOC06_02315) 407081..407992 - 912 WP_215381705.1 oxygen-dependent coproporphyrinogen oxidase -
AOC06_RS02320 (AOC06_02320) 408029..409306 - 1278 WP_215380912.1 phosphoribosylamine--glycine ligase -
AOC06_RS02325 (AOC06_02325) 409319..410038 - 720 WP_215335269.1 YebC/PmpR family DNA-binding transcriptional regulator -
AOC06_RS02335 (AOC06_02335) 410386..410643 + 258 WP_215380913.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
AOC06_RS02340 (AOC06_02340) 410633..410896 + 264 WP_215380914.1 Txe/YoeB family addiction module toxin Toxin
AOC06_RS02345 (AOC06_02345) 410901..411842 - 942 WP_215335271.1 CysB family HTH-type transcriptional regulator -
AOC06_RS02350 (AOC06_02350) 411906..413060 - 1155 WP_215380917.1 LPS export ABC transporter permease LptG -
AOC06_RS02355 (AOC06_02355) 413057..414172 - 1116 WP_215380919.1 LPS export ABC transporter permease LptF -
AOC06_RS02360 (AOC06_02360) 414296..415873 + 1578 WP_215380921.1 leucyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10224.89 Da        Isoelectric Point: 9.9410

>T172316 WP_215380914.1 NZ_CP061298:410633-410896 [Polynucleobacter paludilacus]
MRSKLVWTTAAWSDYLYWQGQDKKTLKRINLLIKDAMRNPEAGIGKPEALKENLSGLWSRRIDDVNRLVYVVEKDQLVII
ACRYHYA

Download         Length: 264 bp

>T172316 NZ_CP079725:c2739246-2737924 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCACCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9593.98 Da        Isoelectric Point: 8.5492

>AT172316 WP_215380913.1 NZ_CP061298:410386-410643 [Polynucleobacter paludilacus]
MRVINFSDARNQFKQVIDQVVADSDVTIISRRDADDAVVMSLDTYNSMMEAVHLLKSPANVKHLEKSLAQYRKGQTKAKA
LVDEK

Download         Length: 258 bp

>AT172316 NZ_CP079725:c2739512-2739246 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References