Detailed information of TA system TA172274

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2624486..2624817
• Replicon: chromosome
• Accession: NZ_CP061284
• Organism: Bacillus halotolerans strain XH-1

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: ICJ61_RS13615
• Protein ID: WP_024122157.1
• Coordinates: 2624486..2624665 (+)
• Length: 60 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2624589..2624817 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ICJ61_RS13605	2623712..2623849	-	138	WP_021480099.1	hypothetical protein	-
ICJ61_RS13610	2623891..2624340	-	450	WP_024122156.1	phage portal protein	-
ICJ61_RS13615	2624486..2624665	+	180	WP_024122157.1	type I toxin-antitoxin system toxin TxpA	Toxin
-	2624589..2624817	-	229	NuclAT_0	-	Antitoxin
-	2624589..2624817	-	229	NuclAT_0	-	Antitoxin
-	2624589..2624817	-	229	NuclAT_0	-	Antitoxin
-	2624589..2624817	-	229	NuclAT_0	-	Antitoxin
ICJ61_RS13620	2625053..2625142	+	90	WP_075058862.1	type I toxin-antitoxin system toxin BsrH	-
ICJ61_RS13625	2625435..2625878	-	444	WP_003229930.1	phage tail tube protein	-
ICJ61_RS13630	2625881..2627281	-	1401	WP_188323157.1	phage tail sheath family protein	-
ICJ61_RS13635	2627282..2627473	-	192	WP_188323158.1	hypothetical protein	-
ICJ61_RS13640	2627470..2627907	-	438	WP_188323159.1	phage portal protein	-
ICJ61_RS13645	2627920..2628423	-	504	WP_188323160.1	HK97 gp10 family phage protein	-
ICJ61_RS13650	2628420..2628782	-	363	WP_188323161.1	YqbH/XkdH family protein	-
ICJ61_RS13655	2628779..2629174	-	396	WP_004398566.1	DUF3199 family protein	-
ICJ61_RS13660	2629178..2629489	-	312	WP_188323162.1	YqbF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2605805..2648588	42783

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 60 a.a.
• Molecular weight: 6739.19 Da
• Isoelectric Point: 8.0370

>T172274 WP_024122157.1 NZ_CP061284:2624486-2624665 [Bacillus halotolerans]
MSTYESLMVMIGFANLIGGIMTWVLSLLTLLFMLRKKDTHPIYITVKEKCLHEDPPIKG

Nucleotide

• Length: 180 bp

>T172274 NZ_CP079712:3466072-3466650 [Pseudomonas aeruginosa]
ATGTCCCTCGAACTGCTGAGCAACCGCCTCGAATTCCTCCGCGAAGCCGAACGCCTGAAAGACGTCCTGCGCTCCGCGCA
CACCTCCTCCGGCCGCCCGGAAAGCACCGCCGAACATAGCTGGCGGCTGTGCCTGATGGCACTGGCCTTCGAGGACCAAC
TGGCCGGCCTGGACCTCGGCAAGGTCCTGCGCATGTGCGTGGTCCACGACCTCGGCGAAGCGATCCACGGCGACATCCCC
GCCGTCGAGCAGGCCGCGCACCCGGACAAAGGCGAACAGGAACGCGCCGACCTGTTGCAGCTGACCCGTCACCTCGACGC
TCCGCTGCGCGACCGCCTGCTCGCCCTGTGGGACGAATACGAGCGCGGCGAGTCCGCCGAAGCCCTGGCAGTGAAGGCCC
TGGACAAGCTGGAAACCCTGCTCCAGCACACCCAGGGCGACAATCCGGCGGACTTCGACTATGCCTTCAACCTCGACTAC
GGCCGTCGCTATACCGACCGCGCACCGCTGTTCAAGACCCTGCGCGAGCTACTCGACGCCAGGACCCGACAGCGCCTCGC
AGTTCGGCGCGACGCCTAG

Antitoxin

Nucleotide

• Length: 229 bp

>AT172274 NZ_CP061284:c2624817-2624589 [Bacillus halotolerans]
CAAGCAAAAGTATTGCAACTACTGGCGTAAGCTTATAGTTGGTACCACATTACCACATTACCACAATACAACTTGTTAAT
GTGTGTTACTTTCATGAGAAATGCATAAAATATAAAAGCCAGAGTGTTGCAGCACTCTAGCTTTTAAAGAAACTACCCTT
TAATAGGAGGGTCCTCGTGTAGACACTTTTCCTTTACAGTAATGTAAATAGGATGAGTGTCTTTTTTTC

Structures

Antitoxin