Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3505246..3505754 Replicon chromosome
Accession NZ_CP061170
Organism Microbacterium sp. HY82

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HCR84_RS16930 Protein ID WP_166983207.1
Coordinates 3505494..3505754 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HCR84_RS16925 Protein ID WP_166983208.1
Coordinates 3505246..3505497 (+) Length 84 a.a.

Genomic Context

HCR84_RS16905HCR84_RS16910HCR84_RS16915HCR84_RS16920HCR84_RS16925HCR84_RS16930HCR84_RS16935HCR84_RS16950HCR84_RS16955HCR84_RS16940HCR84_RS16945
Location: 3500338..3501639 (1302 bp)
Type: Others
Protein ID: WP_166983211.1
Location: 3501818..3502978 (1161 bp)
Type: Others
Protein ID: WP_166983297.1
Location: 3502975..3503574 (600 bp)
Type: Others
Protein ID: WP_166983210.1
Location: 3503755..3505131 (1377 bp)
Type: Others
Protein ID: WP_166983209.1
Location: 3505246..3505497 (252 bp)
Type: Antitoxin
Protein ID: WP_166983208.1
Location: 3505494..3505754 (261 bp)
Type: Toxin
Protein ID: WP_166983207.1
Location: 3505862..3507172 (1311 bp)
Type: Others
Protein ID: WP_166983206.1
Location: 3508086..3509495 (1410 bp)
Type: Others
Protein ID: WP_166983203.1
Location: 3509619..3510626 (1008 bp)
Type: Others
Protein ID: WP_166983202.1
Location: 3507240..3507647 (408 bp)
Type: Others
Protein ID: WP_166983205.1
Location: 3507666..3507944 (279 bp)
Type: Others
Protein ID: WP_166983204.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR84_RS169053500338..3501639+1302WP_166983211.1alpha-galactosidase-
HCR84_RS169103501818..3502978+1161WP_166983297.1MFS transporter-
HCR84_RS169153502975..3503574+600WP_166983210.1hypothetical protein-
HCR84_RS169203503755..3505131+1377WP_166983209.1MHS family MFS transporter-
HCR84_RS169253505246..3505497+252WP_166983208.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HCR84_RS169303505494..3505754+261WP_166983207.1Txe/YoeB family addiction module toxinToxin
HCR84_RS169353505862..3507172+1311WP_166983206.1GNAT family N-acetyltransferase-
HCR84_RS169403507240..3507647-408WP_166983205.1DUF3592 domain-containing protein-
HCR84_RS169453507666..3507944-279WP_166983204.1hypothetical protein-
HCR84_RS169503508086..3509495+1410WP_166983203.1aldehyde dehydrogenase family protein-
HCR84_RS169553509619..3510626+1008WP_166983202.1helix-turn-helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10430.82 Da        Isoelectric Point: 9.6925

>T172164 WP_166983207.1 NZ_CP061170:3505494-3505754 [Microbacterium sp. HY82]
VRYVWDEDAWADYVWWQVQDRKVLKRINALLRDVARNGNEGIGKPEPLKHGFRGYWSRRITDEHRLVYKIVDDEVRVAAC
RYHYGR

Download         Length: 261 bp

>T172164 NZ_CP079632:32970-33386 [Klebsiella pneumoniae subsp. pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9564.61 Da        Isoelectric Point: 4.4663

>AT172164 WP_166983208.1 NZ_CP061170:3505246-3505497 [Microbacterium sp. HY82]
MRTMSYSESRANYAETLSKVVDDREEVVITRSGHEPVVIVSLDDYESLKETAYLLRNPENARRLMRSIERLDTGEGTERD
LAE

Download         Length: 252 bp

>AT172164 NZ_CP079632:32743-32973 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References