Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 903837..904345 Replicon chromosome
Accession NZ_CP061170
Organism Microbacterium sp. HY82

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HCR84_RS04360 Protein ID WP_166984093.1
Coordinates 903837..904097 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HCR84_RS04365 Protein ID WP_166984092.1
Coordinates 904094..904345 (-) Length 84 a.a.

Genomic Context

HCR84_RS04335HCR84_RS04355HCR84_RS04370HCR84_RS04375HCR84_RS04380HCR84_RS04385HCR84_RS04390HCR84_RS04395HCR84_RS04400HCR84_RS04340HCR84_RS04345HCR84_RS04350HCR84_RS04360HCR84_RS04365
Location: 899996..901054 (1059 bp)
Type: Others
Protein ID: WP_166984098.1
Location: 903322..903624 (303 bp)
Type: Others
Protein ID: WP_166984094.1
Location: 904747..905274 (528 bp)
Type: Others
Protein ID: WP_166984091.1
Location: 905271..905624 (354 bp)
Type: Others
Protein ID: WP_166984090.1
Location: 905624..905941 (318 bp)
Type: Others
Protein ID: WP_166984089.1
Location: 906389..906862 (474 bp)
Type: Others
Protein ID: WP_166984088.1
Location: 907222..907818 (597 bp)
Type: Others
Protein ID: WP_166984087.1
Location: 907908..908417 (510 bp)
Type: Others
Protein ID: WP_166984086.1
Location: 908549..909058 (510 bp)
Type: Others
Protein ID: WP_166984085.1
Location: 901483..901755 (273 bp)
Type: Others
Protein ID: WP_166984097.1
Location: 901739..901969 (231 bp)
Type: Others
Protein ID: WP_166984096.1
Location: 902209..903138 (930 bp)
Type: Others
Protein ID: WP_166984095.1
Location: 903837..904097 (261 bp)
Type: Toxin
Protein ID: WP_166984093.1
Location: 904094..904345 (252 bp)
Type: Antitoxin
Protein ID: WP_166984092.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HCR84_RS04335899996..901054+1059WP_166984098.1FUSC family protein-
HCR84_RS04340901483..901755-273WP_166984097.1type II toxin-antitoxin system RelE/ParE family toxin-
HCR84_RS04345901739..901969-231WP_166984096.1antitoxin-
HCR84_RS04350902209..903138-930WP_166984095.1CPBP family intramembrane metalloprotease-
HCR84_RS04355903322..903624+303WP_166984094.1hypothetical protein-
HCR84_RS04360903837..904097-261WP_166984093.1Txe/YoeB family addiction module toxinToxin
HCR84_RS04365904094..904345-252WP_166984092.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
HCR84_RS04370904747..905274+528WP_166984091.1TetR/AcrR family transcriptional regulator-
HCR84_RS04375905271..905624+354WP_166984090.1QacE family quaternary ammonium compound efflux SMR transporter-
HCR84_RS04380905624..905941+318WP_166984089.1QacE family quaternary ammonium compound efflux SMR transporter-
HCR84_RS04385906389..906862+474WP_166984088.1GNAT family N-acetyltransferase-
HCR84_RS04390907222..907818+597WP_166984087.1hypothetical protein-
HCR84_RS04395907908..908417+510WP_166984086.1GrpB family protein-
HCR84_RS04400908549..909058+510WP_166984085.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10205.59 Da        Isoelectric Point: 8.4536

>T172159 WP_166984093.1 NZ_CP061170:c904097-903837 [Microbacterium sp. HY82]
MSRALAFDKNGWEDYVYWQTQDRKTLKRINTLIADVLRDPFTGIGKPEPLKHILSGAWSRRIDETNRLVYYVTDDHIVIL
QARDHY

Download         Length: 261 bp

>T172159 NZ_CP079629:c4939106-4938822 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9265.34 Da        Isoelectric Point: 4.8259

>AT172159 WP_166984092.1 NZ_CP061170:c904345-904094 [Microbacterium sp. HY82]
MPAITATEARKSLFGLIQRVNDDHTAVEVVSKHGNAVILSKDDYDAITETAYLLRNSANAERLLDAIERARRGEFEQHDL
LEA

Download         Length: 252 bp

>AT172159 NZ_CP079629:c4939338-4939096 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References