Detailed information of TA system TA172103

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 3952298..3952556
• Replicon: chromosome
• Accession: NZ_CP061101
• Organism: Escherichia coli strain 1EC213

Toxin (Protein)

• Gene name: hokC
• Uniprot ID: -
• Locus tag: IB009_RS19195
• Protein ID: WP_000809172.1
• Coordinates: 3952404..3952556 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokC
Locus tag	-
Coordinates	3952298..3952355 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IB009_RS19175	3947324..3948676	+	1353	Protein_3748	fimbria/pilus outer membrane usher protein	-
IB009_RS19180	3948689..3949648	+	960	Protein_3749	fimbrial family protein	-
IB009_RS19185	3949687..3950586	-	900	WP_199206689.1	transcriptional activator NhaR	-
IB009_RS19190	3950652..3951818	-	1167	WP_000681359.1	Na+/H+ antiporter NhaA	-
-	3952298..3952355	-	58	-	-	Antitoxin
IB009_RS19195	3952404..3952556	+	153	WP_000809172.1	type I toxin-antitoxin system toxin MokC	Toxin
IB009_RS19200	3952660..3953790	-	1131	WP_001118464.1	molecular chaperone DnaJ	-
IB009_RS19205	3953879..3955795	-	1917	WP_000516135.1	molecular chaperone DnaK	-
IB009_RS19210	3956172..3956576	+	405	WP_001584154.1	DUF2541 family protein	-
IB009_RS19215	3956602..3957315	+	714	WP_001102385.1	acidic protein MsyB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5529.62 Da
• Isoelectric Point: 7.1312

>T172103 WP_000809172.1 NZ_CP061101:3952404-3952556 [Escherichia coli]
MKQHKAMIVALIVICITAVVAVLVTRKDLCEVHIRTGQTEVAVFTAYESE

Nucleotide

• Length: 153 bp

>T172103 NZ_CP079225:c5150540-5150292 [Rhodococcus sp. LW-XY12]
ATGGCTGCCATCACTGCTACCGAAGCGAGAAAAAACTTCTTTCCGCTGCTCGAACAGGTCAACAAGGACCACACCCCTGT
GGAAATCGTATCCAAGCGGGGCAATGCCGTCCTGATGTCGAAGGATGACTACGACGCCATGCTCGAGACCTCGTACCTGA
TGCAGTCTCCGGCCAACGCCCGACGACTGCTCGCCAGCATGCAGAGAGCTCGCGGAGGTGAATACACCGAAAGGGAACTC
ATCGAGTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT172103 NZ_CP061101:c3952355-3952298 [Escherichia coli]
GTTCAGCATATAGGGGGCCTCGGGTTGATAGTAAAATATCACTCGGGGCTTTTCTCTA

Structures

Antitoxin