Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | prlF-yhaV (relBE)/YhaV-PrlF |
| Location | 349541..350362 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP061084 | ||
| Organism | Pantoea sp. MT58 | ||
Toxin (Protein)
| Gene name | yhaV | Uniprot ID | E0LTA2 |
| Locus tag | IAI47_RS20500 | Protein ID | WP_008924722.1 |
| Coordinates | 349541..350011 (-) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | prlF | Uniprot ID | E0LTA3 |
| Locus tag | IAI47_RS20505 | Protein ID | WP_003851503.1 |
| Coordinates | 350018..350362 (-) | Length | 115 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IAI47_RS20490 | 344867..347269 | + | 2403 | WP_187961286.1 | maltodextrin phosphorylase | - |
| IAI47_RS20495 | 347278..349353 | + | 2076 | WP_008924721.1 | 4-alpha-glucanotransferase | - |
| IAI47_RS20500 | 349541..350011 | - | 471 | WP_008924722.1 | type II toxin-antitoxin system YhaV family toxin | Toxin |
| IAI47_RS20505 | 350018..350362 | - | 345 | WP_003851503.1 | type II toxin-antitoxin system PrlF family antitoxin | Antitoxin |
| IAI47_RS20510 | 350862..351800 | - | 939 | WP_008924723.1 | maltose operon protein MalM | - |
| IAI47_RS20515 | 351904..353205 | - | 1302 | WP_008924724.1 | maltoporin | - |
| IAI47_RS20520 | 353249..354358 | - | 1110 | WP_003851511.1 | maltose/maltodextrin ABC transporter ATP-binding protein MalK | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | pla | 1..522095 | 522095 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 18268.69 Da Isoelectric Point: 7.9495
>T172072 WP_008924722.1 NZ_CP061084:c350011-349541 [Pantoea sp. MT58]
MEDGTVMNGWHVYVHPCFESQLIALTNEVESLRAKYPESYQRIATTKLLAAVFKVINSEICADSHHAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWDNTNS
MEDGTVMNGWHVYVHPCFESQLIALTNEVESLRAKYPESYQRIATTKLLAAVFKVINSEICADSHHAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKTIILAWMNDAETKRAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWDNTNS
Download Length: 471 bp
>T172072 NZ_CP079186:2056528-2056630 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 115 a.a. Molecular weight: 12311.00 Da Isoelectric Point: 4.2091
>AT172072 WP_003851503.1 NZ_CP061084:c350362-350018 [Pantoea sp. MT58]
MGTLTHTNISLRATSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLITRQETVTDDDPVMASFLSFLAADMCNT
PSNIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE
MGTLTHTNISLRATSKLTARSQTTIPAAVRDAMNLQPGENIEYAVLPGGKVLITRQETVTDDDPVMASFLSFLAADMCNT
PSNIKTLDRGLLTRITSLTEGMDVDLDAPLMDDE
Download Length: 345 bp
>AT172072 NZ_CP079186:c2056637-2056492 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|