Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 358580..358741 Replicon chromosome
Accession NZ_CP061041
Organism Staphylococcus warneri strain WS479

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag IAR39_RS01725 Protein ID WP_015364873.1
Coordinates 358646..358741 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 358580..358614 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAR39_RS01695 353610..354833 - 1224 WP_058710123.1 ABC transporter permease -
IAR39_RS01700 354826..355566 - 741 WP_002466806.1 ABC transporter ATP-binding protein -
IAR39_RS01705 355698..356123 + 426 WP_058710124.1 HIT family protein -
IAR39_RS01710 356201..356572 + 372 WP_119548081.1 YtxH domain-containing protein -
IAR39_RS01715 356767..357324 + 558 WP_119548079.1 DUF3267 domain-containing protein -
IAR39_RS01720 357502..358494 + 993 WP_002466825.1 peptidylprolyl isomerase -
- 358580..358614 + 35 - - Antitoxin
IAR39_RS01725 358646..358741 - 96 WP_015364873.1 type I toxin-antitoxin system Fst family toxin Toxin
IAR39_RS01730 358896..359837 - 942 WP_002466800.1 3'-5' exoribonuclease YhaM -
IAR39_RS01735 359837..362770 - 2934 WP_187835297.1 AAA family ATPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3610.26 Da        Isoelectric Point: 8.0878

>T171960 WP_015364873.1 NZ_CP061041:c358741-358646 [Staphylococcus warneri]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Download         Length: 96 bp

>T171960 NZ_CP079120:4698122-4698505 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 35 bp

>AT171960 NZ_CP061041:358580-358614 [Staphylococcus warneri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References