Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 824258..824775 Replicon chromosome
Accession NZ_CP061035
Organism Sphingomonas sp. DH-S5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag H5J25_RS03605 Protein ID WP_202094786.1
Coordinates 824509..824775 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag H5J25_RS03600 Protein ID WP_202094785.1
Coordinates 824258..824512 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5J25_RS03575 819809..820771 - 963 WP_202094781.1 XdhC family protein -
H5J25_RS03580 821020..822000 + 981 WP_202095968.1 glycerophosphodiester phosphodiesterase -
H5J25_RS03585 822003..822281 + 279 WP_202094782.1 hypothetical protein -
H5J25_RS03590 822569..823303 - 735 WP_202094783.1 alpha/beta hydrolase -
H5J25_RS03595 823302..824198 + 897 WP_202094784.1 phenylalanine 4-monooxygenase -
H5J25_RS03600 824258..824512 + 255 WP_202094785.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
H5J25_RS03605 824509..824775 + 267 WP_202094786.1 Txe/YoeB family addiction module toxin Toxin
H5J25_RS03610 824794..825741 - 948 WP_202094787.1 50S ribosomal protein L11 methyltransferase -
H5J25_RS03615 825731..826435 - 705 WP_202094788.1 SDR family oxidoreductase -
H5J25_RS03620 826502..827875 - 1374 WP_202094789.1 chemotaxis protein -
H5J25_RS03625 827910..829253 - 1344 WP_202095970.1 chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10372.95 Da        Isoelectric Point: 10.2669

>T171955 WP_202094786.1 NZ_CP061035:824509-824775 [Sphingomonas sp. DH-S5]
MKLVFSDLAWDQYRYWIDADPKVFAKLNALIVETRRTPFKGTGKPEPLKGDLAGWWSRRITRADRLVYRVSGKSPDQQLE
IAQCRFHY

Download         Length: 267 bp

>T171955 NZ_CP079120:633068-633385 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9289.56 Da        Isoelectric Point: 4.5388

>AT171955 WP_202094785.1 NZ_CP061035:824258-824512 [Sphingomonas sp. DH-S5]
MQVVNYTDARANLKDVMDRVVDDHEEVIVTRKNGKPVVMMSLDEWNSIRETMYLISTPANAGALRASIAQLDAGGGTERT
LIEP

Download         Length: 255 bp

>AT171955 NZ_CP079120:633378-633665 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCAACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References