Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1487393..1487898 Replicon chromosome
Accession NZ_CP061032
Organism Corynebacterium sp. zg-917

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag IAU68_RS07440 Protein ID WP_171192679.1
Coordinates 1487393..1487647 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag IAU68_RS07445 Protein ID WP_171192680.1
Coordinates 1487647..1487898 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAU68_RS07415 1482843..1483508 + 666 WP_171192674.1 peroxide stress protein YaaA -
IAU68_RS07420 1483492..1484349 - 858 WP_171192675.1 hypothetical protein -
IAU68_RS07425 1484596..1485318 + 723 WP_171192676.1 DUF1648 domain-containing protein -
IAU68_RS07430 1485323..1486543 - 1221 WP_171192677.1 sodium/glutamate symporter -
IAU68_RS07435 1486668..1487396 + 729 WP_171192678.1 NAD-dependent deacylase -
IAU68_RS07440 1487393..1487647 - 255 WP_171192679.1 Txe/YoeB family addiction module toxin Toxin
IAU68_RS07445 1487647..1487898 - 252 WP_171192680.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
IAU68_RS07450 1487940..1488890 - 951 WP_171192681.1 methyltransferase -
IAU68_RS07455 1488874..1489614 - 741 WP_171192682.1 uroporphyrinogen-III C-methyltransferase -
IAU68_RS07460 1489639..1490844 + 1206 WP_171192683.1 YdiU family protein -
IAU68_RS07465 1490860..1492356 - 1497 WP_171192684.1 malate dehydrogenase (quinone) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-65)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9988.39 Da        Isoelectric Point: 9.3936

>T171947 WP_171192679.1 NZ_CP061032:c1487647-1487393 [Corynebacterium sp. zg-917]
VRLVWTDDAWSDYLHWQSNDRKTLKRVNQLLKDMLRDPFEGIGKPEPLKYGAEGAWSRRITQEHRLVYMVSGGDLVILQA
RYHY

Download         Length: 255 bp

>T171947 NZ_CP079115:4198816-4199034 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9378.30 Da        Isoelectric Point: 4.3646

>AT171947 WP_171192680.1 NZ_CP061032:c1487898-1487647 [Corynebacterium sp. zg-917]
MSISASEARRTLYPLIERVNNDRDAVEIVSRNGNAVLMAAEDYEAWVETAYLFKSRENARRLTRSYDDALNGAVSEHDVD
LDA

Download         Length: 252 bp

>AT171947 NZ_CP079115:4198415-4198789 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References