Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2273318..2273474 Replicon chromosome
Accession NZ_CP061029
Organism Staphylococcus epidermidis strain Z0118SE0132

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag IAU62_RS10900 Protein ID WP_099560939.1
Coordinates 2273318..2273413 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2273438..2273474 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IAU62_RS10875 2269482..2271110 + 1629 WP_061642462.1 recombinase family protein -
IAU62_RS10880 2271615..2271965 + 351 WP_061544230.1 hypothetical protein -
IAU62_RS10885 2272052..2272363 + 312 WP_061544231.1 hypothetical protein -
IAU62_RS10890 2272378..2272881 + 504 WP_037559702.1 DUF1643 domain-containing protein -
IAU62_RS10895 2272896..2273117 + 222 WP_061544232.1 hypothetical protein -
IAU62_RS10900 2273318..2273413 + 96 WP_099560939.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2273438..2273474 - 37 - - Antitoxin
IAU62_RS10905 2273783..2275021 - 1239 WP_061544233.1 restriction endonuclease subunit S -
IAU62_RS10910 2275014..2276570 - 1557 WP_061544234.1 type I restriction-modification system subunit M -
IAU62_RS10915 2276571..2277152 - 582 WP_061544235.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3503.15 Da        Isoelectric Point: 7.9875

>T171938 WP_099560939.1 NZ_CP061029:2273318-2273413 [Staphylococcus epidermidis]
MADILVNIMTTAASGCIVALFSYWLRKRDDK

Download         Length: 96 bp

>T171938 NZ_CP079110:c1046596-1046471 [Nosocomiicoccus ampullae]
CTGAATGAATATTGGAGATATCGTATAGGAAAATACAGAATAATAACTAGAATTGATGATGATAAAATTATTATTAATAT
CATTTCTGTAGGGCATCGTTCAAATATTTATAAAAAAAACATTTAA

Antitoxin


Download         Length: 37 bp

>AT171938 NZ_CP061029:c2273474-2273438 [Staphylococcus epidermidis]
ATGCACCAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References