Detailed information of TA system TA171011

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 1488656..1488850
• Replicon: chromosome
• Accession: NZ_CP060804
• Organism: Enterococcus faecalis strain SF28073

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: H9Q64_RS08230
• Protein ID: WP_015543884.1
• Coordinates: 1488656..1488751 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	1488786..1488850 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H9Q64_RS08210	1483833..1484948	+	1116	WP_002383680.1	FAD-binding oxidoreductase	-
H9Q64_RS08215	1485017..1486171	-	1155	WP_002383679.1	mannitol-1-phosphate 5-dehydrogenase	-
H9Q64_RS08220	1486186..1486623	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
H9Q64_RS08225	1486638..1488410	-	1773	WP_010715007.1	PTS mannitol transporter subunit IICBA	-
H9Q64_RS08230	1488656..1488751	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	1488786..1488850	-	65	NuclAT_9	-	Antitoxin
H9Q64_RS08235	1489021..1489455	-	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
H9Q64_RS08240	1489466..1491499	-	2034	WP_002383677.1	transcription antiterminator	-
H9Q64_RS08245	1491490..1493238	-	1749	WP_002383675.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T171011 WP_015543884.1 NZ_CP060804:1488656-1488751 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T171011 NZ_CP077814:1912662-1913195 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT171011 NZ_CP060804:c1488850-1488786 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin