Detailed information of TA system TA170973

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 383783..383977
• Replicon: chromosome
• Accession: NZ_CP060796
• Organism: Enterococcus faecalis strain EF-2001

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: H8446_RS02110
• Protein ID: WP_015543884.1
• Coordinates: 383882..383977 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	383783..383847 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H8446_RS02095	379408..381156	+	1749	WP_192847543.1	PTS transporter subunit EIIC	-
H8446_RS02100	381147..383180	+	2034	WP_002355275.1	BglG family transcription antiterminator	-
H8446_RS02105	383191..383625	+	435	WP_010711967.1	PTS sugar transporter subunit IIA	-
-	383783..383847	+	65	-	-	Antitoxin
H8446_RS02110	383882..383977	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
H8446_RS02115	384223..385995	+	1773	WP_010711968.1	PTS mannitol-specific transporter subunit IIBC	-
H8446_RS02120	386010..386447	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
H8446_RS02125	386462..387616	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
H8446_RS02130	387685..388800	-	1116	WP_077932733.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T170973 WP_015543884.1 NZ_CP060796:c383977-383882 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T170973 NZ_CP077809:635463-635996 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTATTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT170973 NZ_CP060796:383783-383847 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCAGTAGGGTGTCTTTTTTT

Structures

Antitoxin