Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1089130..1089635 Replicon chromosome
Accession NZ_CP060789
Organism Tessaracoccus defluvii strain JCM 17540

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag H9L22_RS05115 Protein ID WP_182781594.1
Coordinates 1089130..1089396 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag H9L22_RS05120 Protein ID WP_187721853.1
Coordinates 1089393..1089635 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9L22_RS05085 1084496..1085068 + 573 WP_187722572.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein -
H9L22_RS05090 1085065..1085991 + 927 WP_187721849.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
H9L22_RS05095 1086031..1086909 - 879 WP_187721850.1 DUF262 domain-containing protein -
H9L22_RS05100 1086969..1087295 + 327 WP_187722789.1 hypothetical protein -
H9L22_RS05105 1087882..1088064 + 183 WP_187721851.1 hypothetical protein -
H9L22_RS05110 1088233..1088523 - 291 WP_187721852.1 hypothetical protein -
H9L22_RS05115 1089130..1089396 - 267 WP_182781594.1 Txe/YoeB family addiction module toxin Toxin
H9L22_RS05120 1089393..1089635 - 243 WP_187721853.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H9L22_RS05125 1089994..1090980 + 987 WP_187721854.1 hypothetical protein -
H9L22_RS05130 1092487..1092750 - 264 WP_187721855.1 type II toxin-antitoxin system RelE/ParE family toxin -
H9L22_RS05135 1092747..1093019 - 273 WP_187721856.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
H9L22_RS05140 1093003..1094145 - 1143 WP_187721857.1 site-specific integrase -
H9L22_RS05145 1094207..1094539 - 333 WP_187721858.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1083654..1097164 13510


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10240.83 Da        Isoelectric Point: 9.7544

>T170962 WP_182781594.1 NZ_CP060789:c1089396-1089130 [Tessaracoccus defluvii]
VSPWTLVYSRQAQKDAQKLASSGLKTKAQHLLEVLAQDPFTTPPKYEKLVGDLAGCYSRRINIQHRLVYEVLPDRHVVHI
LRMWTHYE

Download         Length: 267 bp

>T170962 NZ_CP077806:c3421455-3421171 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGACCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8705.62 Da        Isoelectric Point: 3.9421

>AT170962 WP_187721853.1 NZ_CP060789:c1089635-1089393 [Tessaracoccus defluvii]
MTAVSATSARANLYRLIDQVNEESEPLTITGQRGNAVLIGEEDWLAIQETLFLESVPGLADSIRRSRAEGVDAGSTELDW

Download         Length: 243 bp

>AT170962 NZ_CP077806:c3421687-3421445 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCAGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References