Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3151348..3152048 Replicon chromosome
Accession NZ_CP060711
Organism Thermomonas brevis strain KACC 16975

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag H9L17_RS14565 Protein ID WP_187570137.1
Coordinates 3151348..3151650 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag H9L17_RS14570 Protein ID WP_187570138.1
Coordinates 3151653..3152048 (+) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9L17_RS14540 3146399..3146914 + 516 WP_187570132.1 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA -
H9L17_RS14545 3146916..3148124 + 1209 WP_187570133.1 beta-ketoacyl-ACP synthase I -
H9L17_RS14550 3148246..3149100 - 855 WP_187570134.1 alpha/beta fold hydrolase -
H9L17_RS14555 3149132..3150865 - 1734 WP_187570135.1 STAS domain-containing protein -
H9L17_RS14560 3150865..3151119 - 255 WP_187570136.1 helix-turn-helix domain-containing protein -
H9L17_RS14565 3151348..3151650 + 303 WP_187570137.1 type II toxin-antitoxin system MqsR family toxin Toxin
H9L17_RS14570 3151653..3152048 + 396 WP_187570138.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
H9L17_RS14575 3152058..3152943 - 886 Protein_2859 restriction endonuclease -
H9L17_RS14580 3152964..3154361 - 1398 WP_187570139.1 PhoH family protein -
H9L17_RS14585 3154513..3154983 - 471 WP_187570140.1 peroxiredoxin -
H9L17_RS14590 3154989..3155654 - 666 WP_187570141.1 glycine cleavage system protein R -
H9L17_RS14595 3155704..3156606 + 903 WP_187571987.1 4-hydroxy-tetrahydrodipicolinate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-99)

Antitoxin

Cro/C1-type helix-turn-helix domain

(77-127)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11074.01 Da        Isoelectric Point: 10.4528

>T170850 WP_187570137.1 NZ_CP060711:3151348-3151650 [Thermomonas brevis]
MQKGTPHRRLSVVKALIAAGKVRATFKAYRAGRDIGVVDVAGMCEVVMALTPRDFYKSMTSHANHRVWQDVYHGRTAAGI
AVYLKLTVVDDVLIVSFKEL

Download         Length: 303 bp

>T170850 NZ_CP077741:c921739-921551 [Staphylococcus aureus]
ATGTCTTTACATTTTGCAATTCTGTTTTGGCTAGCATTAATTTTCTTAGTTGCCGCTACGTTTATACTCGTATTAATGAA
AAAAACTGGCAAAGAATCTAAAAAAGAGTCCTATTTAAGTTTCACTGTCATTCTCTATATTTTTGGATTCGCTATATTAA
TATACACATTTATATTTGGTGTGCTATAA

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14630.74 Da        Isoelectric Point: 6.2281

>AT170850 WP_187570138.1 NZ_CP060711:3151653-3152048 [Thermomonas brevis]
MICPECGAAELVHDTRDEPYTYKGQTTTIPAVTADYCPVCGEAVLEPVHGDRYSRLIGEFQRRVNATLVDPAYIAGMRRK
LDLDQRQAADIFGGGVNAFSRYETGRTKPPLALVKLLRVLEKHPELLDEIR

Download         Length: 396 bp

>AT170850 NZ_CP077741:c922027-921767 [Staphylococcus aureus]
ATGAATAACATTTTGTTAAATGCTATCAATATAGTTATTACTACCACTTTTGTTATCTTTAATATTTTAATCACATATAA
TAAAGATTTAGATGATTTATGTTGGCTCCTGCCTGGTATTATCATTTGTGGTGTGATACTCATAGTATCCTTTACCATTG
CAATGATAACTAAAAGCTGGTTAAGTGAAATATTATTTTTTATAAATATCGTACTCGTTCTCTATTACATTTATCCTATT
TTTTATAGTTTTATAGGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References