Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3684713..3684935 Replicon chromosome
Accession NZ_CP060708
Organism Escherichia coli strain MFDpir

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag H9446_RS17890 Protein ID WP_000141634.1
Coordinates 3684713..3684820 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3684869..3684935 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9446_RS17865 3679966..3680718 - 753 Protein_3486 cellulose biosynthesis protein BcsQ -
H9446_RS17870 3680730..3680918 - 189 WP_001063318.1 YhjR family protein -
H9446_RS17875 3681191..3682762 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
H9446_RS17880 3682759..3682950 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
H9446_RS17885 3682947..3684626 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
H9446_RS17890 3684713..3684820 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3684869..3684935 + 67 - - Antitoxin
H9446_RS17895 3685296..3686567 + 1272 WP_001295225.1 transporter -
H9446_RS17900 3686597..3687601 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
H9446_RS17905 3687598..3688581 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
H9446_RS17910 3688592..3689494 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T170798 WP_000141634.1 NZ_CP060708:c3684820-3684713 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T170798 NZ_CP077706:3416772-3416990 [Salmonella enterica subsp. enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 67 bp

>AT170798 NZ_CP060708:3684869-3684935 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References