170522

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4748225..4749015 Replicon chromosome
Accession NZ_CP060595
Organism Pseudomonas monteilii strain A2

Toxin (Protein)


Gene name yhaV Uniprot ID A0A0P7CAA7
Locus tag H9H53_RS21835 Protein ID WP_028698629.1
Coordinates 4748548..4749015 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID A0A0P7D0H8
Locus tag H9H53_RS21830 Protein ID WP_016713504.1
Coordinates 4748225..4748551 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9H53_RS21810 4743761..4744822 - 1062 WP_028698627.1 HlyD family secretion protein -
H9H53_RS21815 4744851..4746392 - 1542 WP_016713507.1 MFS transporter -
H9H53_RS21820 4746509..4747414 - 906 WP_235200187.1 LysR family transcriptional regulator -
H9H53_RS21825 4747685..4748131 + 447 WP_016713505.1 universal stress protein -
H9H53_RS21830 4748225..4748551 + 327 WP_016713504.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
H9H53_RS21835 4748548..4749015 + 468 WP_028698629.1 type II toxin-antitoxin system YhaV family toxin Toxin
H9H53_RS21840 4749061..4749921 - 861 WP_016713502.1 HlyD family secretion protein -
H9H53_RS21845 4749932..4750132 - 201 WP_009685040.1 DUF1656 domain-containing protein -
H9H53_RS21850 4750122..4752299 - 2178 WP_019098848.1 FUSC family protein -
H9H53_RS21855 4752296..4753825 - 1530 WP_235200188.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 18080.59 Da        Isoelectric Point: 10.1790

>T170522 WP_028698629.1 NZ_CP060595:4748548-4749015 [Pseudomonas monteilii]
MSDASRKPLVIHGWTVIAHPLFLAKLEALSAQVQAQMHKDPTGYTRRNAYKRLAAIKRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESSDDAYKVFQKMLHTGHPPDDWEQRLREAAAE

Download         Length: 468 bp

>T170522 NZ_CP077422:1919481-1919795 [Dickeya dadantii]
ATGCAATTCACCGTATACGGTAATACCGGGAAAAGCACCATTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAGTTGAATCGTCGGATAGTGATCCCGTTGCTCCCTGTTGAAAAGTACCCGGCAGGCCGCCGACCGGAGCGCTTTGTCC
CCGTCGTCAGGCTGACGGACGGTAAAGAATACGCCGTAATGACGCACGAGCTGGCAAGTATCCCTGTCCAGGCACTGGGG
GCGGTATTCTGTGATGCGTCGCAGTACCGTACTCAGGTGAAGGCTGCAATAGACTTCCTCATCGACGGCATTTAG

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12007.46 Da        Isoelectric Point: 4.3118

>AT170522 WP_016713504.1 NZ_CP060595:4748225-4748551 [Pseudomonas monteilii]
MATTLDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGEVILTRAEATESDPVLGKFLDFLAHDIATNPQRLQVV
DADLIARLDKLVGDAEVDLDQSLSADDE

Download         Length: 327 bp

>AT170522 NZ_CP077422:1919242-1919478 [Dickeya dadantii]
ATGACCGCGAAACAACGTAACACGCAGAGCGTGACCATGACGGTAGAGCGTGCCTTACTGCTCCGGGCGCGTCAGGCGGG
CATTAACCTGAGTGCCACCCTGACAACCGCTCTGGATGCAGAGCTTCGGCACCATGAAGCGAACAAATGGCAGGAAGAGA
ACAGGGAAGCCATCGACGCATTAAACCGTTTTCATGATGAGCACGGCTGTTTCAGCGATGAATACCGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P7CAA7

Antitoxin

Source ID Structure
AlphaFold DB A0A0P7D0H8

References