Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 699662..699941 Replicon chromosome
Accession NZ_CP060584
Organism Staphylococcus aureus strain WH52

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag H9M95_RS03330 Protein ID WP_001802298.1
Coordinates 699662..699766 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF3
Locus tag -
Coordinates 699762..699941 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9M95_RS03305 695046..695828 + 783 WP_000908177.1 ABC transporter ATP-binding protein -
H9M95_RS03310 695896..696753 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
H9M95_RS03315 697458..697550 - 93 WP_001790138.1 hypothetical protein -
H9M95_RS03320 697839..698975 + 1137 WP_000115562.1 SAP domain-containing protein -
H9M95_RS03325 699018..699501 + 484 Protein_653 recombinase family protein -
H9M95_RS03330 699662..699766 + 105 WP_001802298.1 hypothetical protein Toxin
- 699762..699941 - 180 - - Antitoxin
H9M95_RS03335 700266..701357 - 1092 WP_000495671.1 lytic regulatory protein -
H9M95_RS03340 701623..702603 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
H9M95_RS03345 702605..702925 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
H9M95_RS03350 703077..703742 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T170494 WP_001802298.1 NZ_CP060584:699662-699766 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T170494 NZ_CP077411:c2123994-2123891 [Enterobacter asburiae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 180 bp

>AT170494 NZ_CP060584:c699941-699762 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGCAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTC
AAAGCGAATAGAAGGTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References