Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 225110..225690 Replicon chromosome
Accession NZ_CP060436
Organism Pseudooceanicola algae strain Lw-13e

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PSAL_RS01060 Protein ID WP_119838420.1
Coordinates 225110..225391 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag PSAL_RS01065 Protein ID WP_119838421.1
Coordinates 225403..225690 (+) Length 96 a.a.

Genomic Context

PSAL_RS01035PSAL_RS01045PSAL_RS01050PSAL_RS01055PSAL_RS01060PSAL_RS01065PSAL_RS01075PSAL_RS01040PSAL_RS01070
Location: 223529..223660 (132 bp)
Type: Others
Protein ID: WP_119840379.1
Location: 224125..224415 (291 bp)
Type: Others
Protein ID: WP_196941888.1
Location: 224419..224631 (213 bp)
Type: Others
Protein ID: WP_119838418.1
Location: 224724..225017 (294 bp)
Type: Others
Protein ID: WP_196222738.1
Location: 225110..225391 (282 bp)
Type: Toxin
Protein ID: WP_119838420.1
Location: 225403..225690 (288 bp)
Type: Antitoxin
Protein ID: WP_119838421.1
Location: 229228..230304 (1077 bp)
Type: Others
Protein ID: WP_119838422.1
Location: 223861..224070 (210 bp)
Type: Others
Protein ID: Protein_202
Location: 225830..228730 (2901 bp)
Type: Others
Protein ID: WP_119838430.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PSAL_RS01035223529..223660+132WP_119840379.1transposase-
PSAL_RS01040223861..224070-210Protein_202IS3 family transposase-
PSAL_RS01045224125..224415+291WP_196941888.1hypothetical protein-
PSAL_RS01050224419..224631+213WP_119838418.1hypothetical protein-
PSAL_RS01055224724..225017+294WP_196222738.1transposase-
PSAL_RS01060225110..225391+282WP_119838420.1type II toxin-antitoxin system RelE/ParE family toxinToxin
PSAL_RS01065225403..225690+288WP_119838421.1HigA family addiction module antidote proteinAntitoxin
PSAL_RS01070225830..228730-2901WP_119838430.1type I restriction endonuclease subunit R-
PSAL_RS01075229228..230304+1077WP_119838422.1tyrosine-type recombinase/integrase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--223861..224109248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(29-69)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10405.05 Da        Isoelectric Point: 10.2613

>T170374 WP_119838420.1 NZ_CP060436:225110-225391 [Pseudooceanicola algae]
MIQSAKGKLATNALQGKYGKRFPTDLVKRTRAMLTALDAAVVVEDLRFPPGNKLEELKGDRAGQHSVRINGQWRICFVWT
PKGPAEVEIVDYH

Download         Length: 282 bp

>T170374 NZ_CP077304:72534-72863 [Acinetobacter pittii]
ATGTATACAATTGAATATTACAGCGAAGACGTTCAGGATGAGATTCTTACATTACCTGATGGTCTTTTGGCTCGATATTT
TAACTTAACTGACCGTATGGTGATTTACGGCGCAAACTTAGGAGAACCTCACACATTACCAATGAGTAAAGGACTATTTG
AGTTGCGCTTAAAATCTCAAGAAGGTATTGCTCGTGTTATGTATTGCACACTAGTCGGTAAACGCATTGTAATGCTCCAT
AGTTTTGTTAAGAAAACCCAAAAAACACCTAAGCAAGATCTAAACCTAGCACTTGACCGCATGAAAGAGGTGAAAAATGC
GAACACATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10658.34 Da        Isoelectric Point: 4.7440

>AT170374 WP_119838421.1 NZ_CP060436:225403-225690 [Pseudooceanicola algae]
MSLLEDPMHPGEVLKELYLDPLDIGAIGLARRLGVPRTRIERLVKGATSMTPDTALRLAHVFNTTPEYWMNMQTNFDMHA
AIQQIDVSDIEPLVA

Download         Length: 288 bp

>AT170374 NZ_CP077304:72850-73137 [Acinetobacter pittii]
ATGCGAACACATGAAGAAATGAAAGCACTTGCATTATCTCGTTCAGCAGTGCGTACCGAATACGAACGAATTGAACGTGA
AGAAATGCCCCTGCTCGATATGGTACTTACTGCACGTCGAGATGCAGGTCTATCCCAAGCGCAAATCGCGGAACGCATGG
GAACAAGTGTACCTGCCGTTTCACGGCTAGAAAAAGCATTGATCACAGGCAAACCATCACCATCTATTGCCACATTGCAA
AAATATGCTGCGGCAATTGGTAAACATGTTGAAGTGCGTTTTGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References