Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 3096401..3096906 Replicon chromosome
Accession NZ_CP060402
Organism Microbacterium sp. YJN-G

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag H7694_RS14870 Protein ID WP_193599261.1
Coordinates 3096401..3096655 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag H7694_RS14875 Protein ID WP_193597221.1
Coordinates 3096655..3096906 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7694_RS14840 3091675..3092523 - 849 WP_193597215.1 hypothetical protein -
H7694_RS14845 3092590..3092754 - 165 WP_193597216.1 hypothetical protein -
H7694_RS14850 3092893..3093906 - 1014 WP_193597217.1 uroporphyrinogen decarboxylase -
H7694_RS14855 3094012..3095274 + 1263 WP_193597218.1 glutamyl-tRNA reductase -
H7694_RS14860 3095473..3095718 - 246 WP_193597219.1 type II toxin-antitoxin system VapC family toxin -
H7694_RS14865 3095775..3096248 + 474 WP_193597220.1 hypothetical protein -
H7694_RS14870 3096401..3096655 - 255 WP_193599261.1 Txe/YoeB family addiction module toxin Toxin
H7694_RS14875 3096655..3096906 - 252 WP_193597221.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
H7694_RS14880 3096988..3097593 + 606 WP_193597222.1 Fe-S cluster assembly protein HesB -
H7694_RS14885 3097652..3098077 + 426 WP_193597223.1 DUF1801 domain-containing protein -
H7694_RS14890 3098061..3098756 - 696 WP_193597224.1 hypothetical protein -
H7694_RS14895 3098790..3099263 - 474 WP_193597225.1 adenylyltransferase/cytidyltransferase family protein -
H7694_RS14900 3099295..3099825 - 531 WP_193597226.1 hypothetical protein -
H7694_RS14905 3099910..3100770 - 861 WP_193597227.1 extracellular solute-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10156.59 Da        Isoelectric Point: 8.0425

>T170343 WP_193599261.1 NZ_CP060402:c3096655-3096401 [Microbacterium sp. YJN-G]
MRLVWDRSAWEDYVHWQTADRRVLKRINALIDACLRDPFEGIGKPEQLKYGAQGAWSRRITEEHRLVYLVERDDLIVLQA
RYHY

Download         Length: 255 bp

>T170343 NZ_CP077291:3447597-3447815 [Citrobacter farmeri]
ATGTCCGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTGCGACGCTGTCAGACAATTGACACGCTTGAGCGCGT
GATCGAGAAAAATAAATATGAATTGTCTGACAATGAATTGGCTGTATTTTACTCAGCCGCCGATCACCGTCTTGCAGAAT
TGACGATGAATAAACTTTACGACAAGATTCCTTCCTCCGTCTGGAAATTCATCCGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9466.55 Da        Isoelectric Point: 4.5593

>AT170343 WP_193597221.1 NZ_CP060402:c3096906-3096655 [Microbacterium sp. YJN-G]
MSITASEARKTLFPLIERVNADRDAVEIVSRKGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERARAGEVEEHELD
RDE

Download         Length: 252 bp

>AT170343 NZ_CP077291:3447195-3447569 [Citrobacter farmeri]
ATGGATGAATACTCACCCAAAAGACATGATATAGCGCAGCTTAAATTTCTTTGTGAAACGCTTTATCACGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCAATCAACCTTCAACTCAACGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTATAATGAGGACAATAAGCTGATTGAGCAGATTGATGAATATCTG
GACGACACATTTATGTTGTTCAGCAGTTATGGCATTAATGCGCAGGATCTGCAGAAATGGCGGAAATCCGGTAATCGCTT
GTTCCGCTGCTTTGTGAATGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References