Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 1155202..1155808 Replicon chromosome
Accession NZ_CP060390
Organism Psychrobacter sp. KCTC 72983

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PSBA01_RS04925 Protein ID WP_186475225.1
Coordinates 1155473..1155808 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PSBA01_RS04920 Protein ID WP_186475224.1
Coordinates 1155202..1155483 (-) Length 94 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PSBA01_RS04885 1150411..1151286 + 876 WP_186475219.1 N-acetylmuramoyl-L-alanine amidase -
PSBA01_RS04890 1151458..1152204 + 747 WP_186475220.1 pyridoxine 5'-phosphate synthase -
PSBA01_RS04895 1152410..1152535 + 126 Protein_946 L-threonine 3-dehydrogenase -
PSBA01_RS04900 1152696..1152884 + 189 WP_186475221.1 hypothetical protein -
PSBA01_RS04905 1152995..1153645 - 651 WP_186474796.1 IS1595 family transposase -
PSBA01_RS04910 1153750..1154727 - 978 WP_186475222.1 hypothetical protein -
PSBA01_RS04915 1154748..1154981 + 234 WP_186475223.1 hypothetical protein -
PSBA01_RS04920 1155202..1155483 - 282 WP_186475224.1 helix-turn-helix domain-containing protein Antitoxin
PSBA01_RS04925 1155473..1155808 - 336 WP_186475225.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PSBA01_RS04930 1155981..1159982 - 4002 WP_186475226.1 phosphoribosylformylglycinamidine synthase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1152995..1153645 650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(43-106)

Antitoxin

(37-84)


Sequences


Toxin        


Download         Length: 112 a.a.        Molecular weight: 12739.59 Da        Isoelectric Point: 8.3686

>T170260 WP_186475225.1 NZ_CP060390:c1155808-1155473 [Psychrobacter sp. KCTC 72983]
MLHFIETPIFTKQVLKLLDDEAYKELQENLINNPEQGDLIQGAGGVRKTRWALNQGKSGGIRIIYYFVNSQGIFFMLLAY
PKNKQASLSSEEKSGLYKLTQQIKEVYSHEQ

Download         Length: 336 bp

>T170260 NZ_CP077240:c7165-6821 [Acinetobacter pittii]
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAATAACACAAGAGAAAGTCTTAGC
TGCGTTGGTTGTTCTGCAACTGCAAGGACCAAGTTTAGGTCGTCCCTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGAGGTAAACCATTAAGAGCATTTTTTGCATTCGATCCATTACGACAAGCAATT
GTACTGTGTATTGGTGATAAGAGCGGTAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATAAGCAATATGAACT
TCATCTCTCAACATTAGGAGAATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10419.73 Da        Isoelectric Point: 9.8654

>AT170260 WP_186475224.1 NZ_CP060390:c1155483-1155202 [Psychrobacter sp. KCTC 72983]
MSNEFYDDLSTSLNQALAIAKGQTQPSRQFTHDVPSIKEIRTKTGLSQQQFADKLNISSRTLQNWEQGTRNPTGAAVTLM
RLLNKKPELITEA

Download         Length: 282 bp

>AT170260 NZ_CP077240:c6816-6514 [Acinetobacter pittii]
ATGGCTAAGACCCTACAAGAATTATTGGCTAATCGCTCTCCTGAGAGCCAAGCCCGTATTCAAAAAATGGCTGATGAATT
GCTATTAGAAAATCAGCTTTACCTTATTCGTGAAGAACTCGAAATCTCTCAAAAAGAACTGGCTGAAACTTTGGGAATAA
AACAGCCATCGCTTTCAGCAATAGAAAATCGTGGCAATGATCTTAAGATTTCAACCATGAAAAAGTATGTTGAAGCTATG
GGAGGAAAGCTCCGTATTGATGTGGAACTTCCAACTGGGAAACATATAGGATTCAATGTATAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References