Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/RelE-HTH |
Location | 1155202..1155808 | Replicon | chromosome |
Accession | NZ_CP060390 | ||
Organism | Psychrobacter sp. KCTC 72983 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | PSBA01_RS04925 | Protein ID | WP_186475225.1 |
Coordinates | 1155473..1155808 (-) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | PSBA01_RS04920 | Protein ID | WP_186475224.1 |
Coordinates | 1155202..1155483 (-) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PSBA01_RS04885 | 1150411..1151286 | + | 876 | WP_186475219.1 | N-acetylmuramoyl-L-alanine amidase | - |
PSBA01_RS04890 | 1151458..1152204 | + | 747 | WP_186475220.1 | pyridoxine 5'-phosphate synthase | - |
PSBA01_RS04895 | 1152410..1152535 | + | 126 | Protein_946 | L-threonine 3-dehydrogenase | - |
PSBA01_RS04900 | 1152696..1152884 | + | 189 | WP_186475221.1 | hypothetical protein | - |
PSBA01_RS04905 | 1152995..1153645 | - | 651 | WP_186474796.1 | IS1595 family transposase | - |
PSBA01_RS04910 | 1153750..1154727 | - | 978 | WP_186475222.1 | hypothetical protein | - |
PSBA01_RS04915 | 1154748..1154981 | + | 234 | WP_186475223.1 | hypothetical protein | - |
PSBA01_RS04920 | 1155202..1155483 | - | 282 | WP_186475224.1 | helix-turn-helix domain-containing protein | Antitoxin |
PSBA01_RS04925 | 1155473..1155808 | - | 336 | WP_186475225.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PSBA01_RS04930 | 1155981..1159982 | - | 4002 | WP_186475226.1 | phosphoribosylformylglycinamidine synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 1152995..1153645 | 650 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 12739.59 Da Isoelectric Point: 8.3686
>T170260 WP_186475225.1 NZ_CP060390:c1155808-1155473 [Psychrobacter sp. KCTC 72983]
MLHFIETPIFTKQVLKLLDDEAYKELQENLINNPEQGDLIQGAGGVRKTRWALNQGKSGGIRIIYYFVNSQGIFFMLLAY
PKNKQASLSSEEKSGLYKLTQQIKEVYSHEQ
MLHFIETPIFTKQVLKLLDDEAYKELQENLINNPEQGDLIQGAGGVRKTRWALNQGKSGGIRIIYYFVNSQGIFFMLLAY
PKNKQASLSSEEKSGLYKLTQQIKEVYSHEQ
Download Length: 336 bp
>T170260 NZ_CP077240:c7165-6821 [Acinetobacter pittii]
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAATAACACAAGAGAAAGTCTTAGC
TGCGTTGGTTGTTCTGCAACTGCAAGGACCAAGTTTAGGTCGTCCCTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGAGGTAAACCATTAAGAGCATTTTTTGCATTCGATCCATTACGACAAGCAATT
GTACTGTGTATTGGTGATAAGAGCGGTAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATAAGCAATATGAACT
TCATCTCTCAACATTAGGAGAATAA
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAATAACACAAGAGAAAGTCTTAGC
TGCGTTGGTTGTTCTGCAACTGCAAGGACCAAGTTTAGGTCGTCCCTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGAGGTAAACCATTAAGAGCATTTTTTGCATTCGATCCATTACGACAAGCAATT
GTACTGTGTATTGGTGATAAGAGCGGTAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATAAGCAATATGAACT
TCATCTCTCAACATTAGGAGAATAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10419.73 Da Isoelectric Point: 9.8654
>AT170260 WP_186475224.1 NZ_CP060390:c1155483-1155202 [Psychrobacter sp. KCTC 72983]
MSNEFYDDLSTSLNQALAIAKGQTQPSRQFTHDVPSIKEIRTKTGLSQQQFADKLNISSRTLQNWEQGTRNPTGAAVTLM
RLLNKKPELITEA
MSNEFYDDLSTSLNQALAIAKGQTQPSRQFTHDVPSIKEIRTKTGLSQQQFADKLNISSRTLQNWEQGTRNPTGAAVTLM
RLLNKKPELITEA
Download Length: 282 bp
>AT170260 NZ_CP077240:c6816-6514 [Acinetobacter pittii]
ATGGCTAAGACCCTACAAGAATTATTGGCTAATCGCTCTCCTGAGAGCCAAGCCCGTATTCAAAAAATGGCTGATGAATT
GCTATTAGAAAATCAGCTTTACCTTATTCGTGAAGAACTCGAAATCTCTCAAAAAGAACTGGCTGAAACTTTGGGAATAA
AACAGCCATCGCTTTCAGCAATAGAAAATCGTGGCAATGATCTTAAGATTTCAACCATGAAAAAGTATGTTGAAGCTATG
GGAGGAAAGCTCCGTATTGATGTGGAACTTCCAACTGGGAAACATATAGGATTCAATGTATAG
ATGGCTAAGACCCTACAAGAATTATTGGCTAATCGCTCTCCTGAGAGCCAAGCCCGTATTCAAAAAATGGCTGATGAATT
GCTATTAGAAAATCAGCTTTACCTTATTCGTGAAGAACTCGAAATCTCTCAAAAAGAACTGGCTGAAACTTTGGGAATAA
AACAGCCATCGCTTTCAGCAATAGAAAATCGTGGCAATGATCTTAAGATTTCAACCATGAAAAAGTATGTTGAAGCTATG
GGAGGAAAGCTCCGTATTGATGTGGAACTTCCAACTGGGAAACATATAGGATTCAATGTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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