170238

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 27437..28091 Replicon chromosome
Accession NZ_CP060289
Organism Pseudomonas protegens strain H1F10A

Toxin (Protein)


Gene name higB Uniprot ID A0A7G8YM43
Locus tag GGD92_RS00115 Protein ID WP_016965723.1
Coordinates 27741..28091 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GGD92_RS00110 Protein ID WP_179600748.1
Coordinates 27437..27754 (-) Length 106 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GGD92_RS00090 22740..23492 - 753 WP_016965728.1 UDP-2,3-diacylglucosamine diphosphatase -
GGD92_RS00095 23489..23992 - 504 WP_016965727.1 peptidyl-prolyl cis-trans isomerase -
GGD92_RS00100 24263..25963 + 1701 WP_179600746.1 glutamine--tRNA ligase/YqeY domain fusion protein -
GGD92_RS00105 25982..27364 + 1383 WP_016965725.1 cysteine--tRNA ligase -
GGD92_RS00110 27437..27754 - 318 WP_179600748.1 transcriptional regulator Antitoxin
GGD92_RS00115 27741..28091 - 351 WP_016965723.1 hypothetical protein Toxin
GGD92_RS00120 28330..29793 - 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
GGD92_RS00125 29801..31333 - 1533 WP_016965722.1 NADH-quinone oxidoreductase subunit M -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(48-101)


Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 13980.08 Da        Isoelectric Point: 8.9805

>T170238 WP_016965723.1 NZ_CP060289:c28091-27741 [Pseudomonas protegens]
MNALFIELPAFARYRRDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFVDERRNKGKRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T170238 NZ_CP077214:c3652655-3651336 [Aeromonas sp. FDAARGOS 1411]
ATGGCCAATCTGGCTGTCTACATGAACGGCTATCGGGTAGGCACATTCACCAAAACTACCAGCGGCGCCCATCAATTTCA
GTACCGTGAATCATGGCTAGCACAACCGGGCAGCCGTCCGATCTCACTCTCCATGCCATTGCGCCATCAGCCCTACCGGG
GCGATGAAGCCTATAACTTCTTCGATAACCTGCTGCCAGATAATATGGAGGTGAGGAACAGGGTTGTAGCACGCTATCAA
GCGGCATCAACTCAGCCCTTCGATCTGCTCAGTTGCATTGGCCAGGATAGCGTAGGGGCATTACAGCTGGTTACCGAAGG
GCACGATGTTCCAGATGTCAGGCGAATCGACTACAAGGCACTTTCCGATGACGAGCTCGAGCAGATCCTGACCAGCTACA
AATCAGGAATCCCTTTGGGGATGGTCAGGGAGCAAGAGGAGTTCCGGATCTCTATCGCCGGGGCGCAAGAAAAGACTGCG
CTGCTCTATCTCGATGACCGTTGGTACTTGCCACTCAACGCAACGCCGACAACCCACATTATCAAACTCCCTATCGGCAA
GATTGAAAGCCACTCCTACTCGATAGACCTCTCCCAGAGCGTAGAAAACGAATATCTCTGCACTCTGATTGCCAAGGAGT
TTGGTCTACCCGTACCTCACTGCTTCATGATGCAGGTTGGCCAGGTCAAAGCACTGGCTGTGGAACGCTTCGACAGACGT
TACGCTGCCGATCGCAGTTGGATCATGCGCCTTCCCCAAGAAGATTTCTGTCAGGTATTGAATGTTCCGTCAGCACGGAA
ATACGAGAACCATGGAGGACCGGGGATCACTGACATCATGAAAACCTTGCTGGGCTCTGCGACACCAGAACAGGATCGCT
ACCTATTCATGAAATCTCAGGTCCTGTTCTGGCTGCTGGCGGCCACCGATGGCCATGCAAAAAACTTCTCGGTCTTTATT
GAGCCGGAAGGGCGTTTTCGCCTGACCCCTTTTTACGACATCCTATCTGTCTATCCAGTATTTGGCGGCCGAGGCCTCAA
CCGAAGGGACGCCAAGCTCGCTATGGGCCTAGCAAGCAGCAAGGGAAAGAAGTATGCCATTGAGCAGATATTCCCGCGTC
ATTTCTTCCAAACGGCGAAAGCTGTGGGATTTGAGCGTTCTGCTATGGAAGAGATCCTGACAGAACTGGCCAACTCCGTT
GATGATGTTATTGAGCGCGTTACCCAGCAATTGCCAGCAGACTTCCCCGATACCATCAGCAGCACCATTCTAGAGGGCCT
AAAAGCCCGCTCAGCCAGGCTGATAAAGGGTTGGGATTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12038.87 Da        Isoelectric Point: 10.4439

>AT170238 WP_179600748.1 NZ_CP060289:c27754-27437 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLIRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT170238 NZ_CP077214:c3652909-3652655 [Aeromonas sp. FDAARGOS 1411]
ATGAAAGTAACCAGCGCCAAGCAGCTGAGCGCCTGTATCAAGGATGCCAGGCTTTCTCAAAAGCTCTCTCAAGGCAAAGT
GGCCGAGAAAGTGGGGATTAGGCAAGACACAGTCTCCAGCTTCGAGCTCAATCCTGAATCCACCAAGCTGGAGACCCTGT
TCAAGATCCTCGCGGCACTCGAATTGTCACTAGACATCAAGCCCCGCAATGAGTCATCCGATAGTCCGGCATCGGGCTGG
AAGGAGGAGTGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7G8YM43


Antitoxin

Source ID Structure

References