Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4650652..4651352 Replicon chromosome
Accession NZ_CP060288
Organism Pseudomonas mendocina strain CPS5

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag H7683_RS21770 Protein ID WP_209449843.1
Coordinates 4650652..4650948 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag H7683_RS21775 Protein ID WP_183894914.1
Coordinates 4650951..4651352 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7683_RS24530 4645689..4645970 - 282 WP_244973917.1 DUF5447 family protein -
H7683_RS21730 (H7683_21710) 4646124..4646273 - 150 WP_209449836.1 hypothetical protein -
H7683_RS21735 (H7683_21715) 4646270..4646485 - 216 WP_013715705.1 hypothetical protein -
H7683_RS21740 (H7683_21720) 4646966..4648204 + 1239 WP_209449837.1 AAA family ATPase -
H7683_RS21745 (H7683_21725) 4648209..4648991 + 783 WP_209449838.1 hypothetical protein -
H7683_RS21750 (H7683_21730) 4649086..4649856 + 771 WP_209449839.1 hypothetical protein -
H7683_RS21755 (H7683_21735) 4649896..4650198 - 303 WP_209449840.1 hypothetical protein -
H7683_RS21760 (H7683_21740) 4650195..4650350 - 156 WP_209449841.1 hypothetical protein -
H7683_RS21765 (H7683_21745) 4650441..4650683 + 243 WP_209449842.1 hypothetical protein -
H7683_RS21770 (H7683_21750) 4650652..4650948 + 297 WP_209449843.1 type II toxin-antitoxin system MqsR family toxin Toxin
H7683_RS21775 (H7683_21755) 4650951..4651352 + 402 WP_183894914.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
H7683_RS24540 4651726..4651926 + 201 WP_013715702.1 hypothetical protein -
H7683_RS21780 (H7683_21760) 4652034..4653176 + 1143 WP_209449844.1 elongation factor P maturation arginine rhamnosyltransferase EarP -
H7683_RS21785 (H7683_21765) 4653211..4653783 + 573 WP_003240094.1 elongation factor P -
H7683_RS21790 (H7683_21770) 4653861..4654364 + 504 WP_013715699.1 RDD family protein -
H7683_RS21795 (H7683_21775) 4654371..4655321 - 951 WP_209449845.1 LysR family transcriptional regulator -
H7683_RS21800 (H7683_21780) 4655422..4656189 + 768 WP_115291528.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4645391..4657360 11969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11358.13 Da        Isoelectric Point: 7.2009

>T170237 WP_209449843.1 NZ_CP060288:4650652-4650948 [Pseudomonas mendocina]
MEKRKPHFKLELVKQAVADQRYRFTRVALEGGAELGMEMADMLAVISALSSRDFFKSMTTYADHTTWQDVYRPDTEFGQV
YLKFTLVADLLIVSFKEK

Download         Length: 297 bp

>T170237 NZ_CP077213:c26423-25929 [Enterobacter cloacae]
ATGGAATACTTAGAATTAAATGGTTGGAAAATCTGCTTTCACAAATGCTTTTTAGACCAGATTGCGGAGCTTGCGCAGAA
GGTTGCTGAGTTAAAAGCAGCAAAACCCAACGAATACCATAAGAAAAAAGAAACAAAACTCCTGATTGCGATTGAGCGAG
TGATTGAGGAATGGATTGCTTCAGATCCGCTCAATCCACAGTACCGCCAGGGCGACACTTTAGGCGACGAGTACAAACAC
TGGTTCCGGGTAAAATTTTTGCAGCAGTTCCGCTTGTTTTACCGTTGCAGTCAGGAGCACAAAACCATCATTATCGGTTG
GGTTAATGATTTCGATACGCTCCGCGCTTACGGCTCTAAAACGGATGCATATAAAGTGTTTGCGGAAATGCTGAAAGCAG
GTACTCCACCGGATGACTGGAACACACTTCTCAACGCGGCAAAAAAAGCCACGGCCACAAACACTATTCCAGGATTTCTC
ACCAGGCAACCCTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14811.71 Da        Isoelectric Point: 6.4554

>AT170237 WP_183894914.1 NZ_CP060288:4650951-4651352 [Pseudomonas mendocina]
MKCPVCGGAELVHDTRDMPFTYKGQTTQITAVTADWCDACGESLTGPTESERVMRAMNEFRQQVNAQDGNQELIRSVRKQ
LRLSQREAAELFGGGPNAFSRYERGSTEAPQPLVQLFKILGRHPELINELRAG

Download         Length: 402 bp

>AT170237 NZ_CP077213:c26788-26444 [Enterobacter cloacae]
ATGGCTACTCAAATGTTAAATAGTGCGGACGTGTCACTGCGCGCTGAGTCTCGGCTCACCGAACGCAGCCAGACTACGAT
TCCGGCAGCAATACGCGATGCTTTGCATCTCAAGCCAGGTGAGTCCATTCACTATACCTTGCTTGCGGGCGGTAAAGTCA
TCATGTCTAAAAAGGAAGAAGAACAGGACGATCCAGTTGTTCCACAGTTCCTGGCTTTTCTGGAAAACGACATGAAGAAA
AACCCTCAGAATATTGCCCCTGTTCCGGCTCTGTTCTGGGAAAGCATCAAAGCTTTGACTGCTGGAGTTGAAGTTGATTT
AGACGCGCCGCTTACCGATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References