Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 104375..104559 Replicon chromosome
Accession NZ_CP060278
Organism Staphylococcus aureus strain KZN

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag H7684_RS00525 Protein ID WP_000482652.1
Coordinates 104452..104559 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 104375..104435 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H7684_RS00510 99830..99961 - 132 WP_223197975.1 hypothetical protein -
H7684_RS00515 100228..101961 - 1734 WP_000486487.1 ABC transporter ATP-binding protein -
H7684_RS00520 101986..103749 - 1764 WP_001064825.1 ABC transporter ATP-binding protein -
- 104375..104435 + 61 - - Antitoxin
H7684_RS00525 104452..104559 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
H7684_RS00530 104693..105079 - 387 WP_000779360.1 flippase GtxA -
H7684_RS00535 105347..106489 + 1143 WP_001176863.1 glycerate kinase -
H7684_RS00540 106549..107208 + 660 WP_000831298.1 membrane protein -
H7684_RS00545 107390..108601 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
H7684_RS00550 108724..109197 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T170194 WP_000482652.1 NZ_CP060278:c104559-104452 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T170194 NZ_CP077098:c2574932-2574666 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAATTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGACGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 61 bp

>AT170194 NZ_CP060278:104375-104435 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References